Photo-induced copper-catalyzed sequential 1,n-HAT enabling the formation of cyclobutanols

Cyclobutanols are difficult structures to access given their inherent ring strain. Here, the authors present a method to form substituted cyclobutanols from a photocatalytic cascade reaction, proceeding via a 1,5- or 1,6-hydrogen atom transfer and subsequent ring closure.

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Detalles Bibliográficos
Autores principales: Zhusong Cao, Jianye Li, Guozhu Zhang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/5ab5b8e45c8942eaa2d317256a82e822
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Descripción
Sumario:Cyclobutanols are difficult structures to access given their inherent ring strain. Here, the authors present a method to form substituted cyclobutanols from a photocatalytic cascade reaction, proceeding via a 1,5- or 1,6-hydrogen atom transfer and subsequent ring closure.