Human cytomegalovirus-encoded US9 targets MAVS and STING signaling to evade type I interferon immune responses

MAVS and STING signaling are central to interferon-inducing antiviral immunity. Here, the authors show how the human cytomegalovirus protein US9 can evade this immunity by antagonizing these pathways.

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Autores principales: Hyun jin Choi, Areum Park, Sujin Kang, Eunhye Lee, Taeyun A. Lee, Eun A. Ra, Jiseon Lee, Sungwook Lee, Boyoun Park
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/5acb7a2aec44465ea086d375e55ecd0a
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Sumario:MAVS and STING signaling are central to interferon-inducing antiviral immunity. Here, the authors show how the human cytomegalovirus protein US9 can evade this immunity by antagonizing these pathways.