Effects of mechanical stimuli on structure and organization of bone nanocomposites in rats with glucocorticoid-induced osteoporosis

Objective. Clinical use of glucocorticoids is a frequent cause of secondary osteoporosis, which reduces the mineral density of bones and results in pathological fractures. Mechanical stimulation as non-physiological high-frequency vibration with low acceleration prevents the loss of a crystalline co...

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Autores principales:	Kostyshyn Nazar M., Gzhegotskyi Mechyslav R., Kostyshyn Liybov P., Mudry Stepan I.
Formato:	article
Lenguaje:	EN
Publicado:	Sciendo 2021
Materias:	glucocorticosteroids whole body vibration bone remodeling bone mineral density osteoporosis bone nanocomposites x-ray diffraction Diseases of the endocrine glands. Clinical endocrinology RC648-665
Acceso en línea:	https://doaj.org/article/5acf96da401d41889e7a8ad7411d87a8
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id	oai:doaj.org-article:5acf96da401d41889e7a8ad7411d87a8
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spelling	oai:doaj.org-article:5acf96da401d41889e7a8ad7411d87a82021-12-02T16:40:25ZEffects of mechanical stimuli on structure and organization of bone nanocomposites in rats with glucocorticoid-induced osteoporosis1336-032910.2478/enr-2021-0006https://doaj.org/article/5acf96da401d41889e7a8ad7411d87a82021-01-01T00:00:00Zhttps://doi.org/10.2478/enr-2021-0006https://doaj.org/toc/1336-0329Objective. Clinical use of glucocorticoids is a frequent cause of secondary osteoporosis, which reduces the mineral density of bones and results in pathological fractures. Mechanical stimulation as non-physiological high-frequency vibration with low acceleration prevents the loss of a crystalline component and stimulates the anabolic remodeling of the bone. The aim of the present research was to assess the impact of mechanical vibration on the bone structure in rats, which received glucocorticoids.Kostyshyn Nazar M.Gzhegotskyi Mechyslav R.Kostyshyn Liybov P.Mudry Stepan I.Sciendoarticleglucocorticosteroidswhole body vibrationbone remodelingbone mineral densityosteoporosisbone nanocompositesx-ray diffractionDiseases of the endocrine glands. Clinical endocrinologyRC648-665ENEndocrine Regulations, Vol 55, Iss 1, Pp 42-51 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	glucocorticosteroids whole body vibration bone remodeling bone mineral density osteoporosis bone nanocomposites x-ray diffraction Diseases of the endocrine glands. Clinical endocrinology RC648-665
spellingShingle	glucocorticosteroids whole body vibration bone remodeling bone mineral density osteoporosis bone nanocomposites x-ray diffraction Diseases of the endocrine glands. Clinical endocrinology RC648-665 Kostyshyn Nazar M. Gzhegotskyi Mechyslav R. Kostyshyn Liybov P. Mudry Stepan I. Effects of mechanical stimuli on structure and organization of bone nanocomposites in rats with glucocorticoid-induced osteoporosis
description	Objective. Clinical use of glucocorticoids is a frequent cause of secondary osteoporosis, which reduces the mineral density of bones and results in pathological fractures. Mechanical stimulation as non-physiological high-frequency vibration with low acceleration prevents the loss of a crystalline component and stimulates the anabolic remodeling of the bone. The aim of the present research was to assess the impact of mechanical vibration on the bone structure in rats, which received glucocorticoids.
format	article
author	Kostyshyn Nazar M. Gzhegotskyi Mechyslav R. Kostyshyn Liybov P. Mudry Stepan I.
author_facet	Kostyshyn Nazar M. Gzhegotskyi Mechyslav R. Kostyshyn Liybov P. Mudry Stepan I.
author_sort	Kostyshyn Nazar M.
title	Effects of mechanical stimuli on structure and organization of bone nanocomposites in rats with glucocorticoid-induced osteoporosis
title_short	Effects of mechanical stimuli on structure and organization of bone nanocomposites in rats with glucocorticoid-induced osteoporosis
title_full	Effects of mechanical stimuli on structure and organization of bone nanocomposites in rats with glucocorticoid-induced osteoporosis
title_fullStr	Effects of mechanical stimuli on structure and organization of bone nanocomposites in rats with glucocorticoid-induced osteoporosis
title_full_unstemmed	Effects of mechanical stimuli on structure and organization of bone nanocomposites in rats with glucocorticoid-induced osteoporosis
title_sort	effects of mechanical stimuli on structure and organization of bone nanocomposites in rats with glucocorticoid-induced osteoporosis
publisher	Sciendo
publishDate	2021
url	https://doaj.org/article/5acf96da401d41889e7a8ad7411d87a8
work_keys_str_mv	AT kostyshynnazarm effectsofmechanicalstimulionstructureandorganizationofbonenanocompositesinratswithglucocorticoidinducedosteoporosis AT gzhegotskyimechyslavr effectsofmechanicalstimulionstructureandorganizationofbonenanocompositesinratswithglucocorticoidinducedosteoporosis AT kostyshynliybovp effectsofmechanicalstimulionstructureandorganizationofbonenanocompositesinratswithglucocorticoidinducedosteoporosis AT mudrystepani effectsofmechanicalstimulionstructureandorganizationofbonenanocompositesinratswithglucocorticoidinducedosteoporosis
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Effects of mechanical stimuli on structure and organization of bone nanocomposites in rats with glucocorticoid-induced osteoporosis

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