γδ T cells control humoral immune response by inducing T follicular helper cell differentiation

γδ T cells control humoral immune response by inducing T follicular helper cell differentiation

Many immune functions have been reported for γδ T cells, including the regulation of antibody responses. Here the authors show that CXCR5+ γδ T cells release Wnt ligands to initiate the T follicular helper cell differentiation program and promote antibody production.

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Autores principales: Rafael M. Rezende, Amanda J. Lanser, Stephen Rubino, Chantal Kuhn, Nathaniel Skillin, Thais G. Moreira, Shirong Liu, Galina Gabriely, Bruna A. David, Gustavo B. Menezes, Howard L. Weiner
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Science
Q
Acceso en línea:https://doaj.org/article/5adbc105176d41f49ebebc1453323bb6
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