Generation of functional liver organoids on combining hepatocytes and cholangiocytes with hepatobiliary connections ex vivo
Combining mouse hepatocyte progenitors and cholangiocytes ex vivo, the authors form an organoid that can drain bile ex vivo and transport metabolites, as in the liver.
Guardado en:
Autores principales: | Naoki Tanimizu, Norihisa Ichinohe, Yasushi Sasaki, Tohru Itoh, Ryo Sudo, Tomoko Yamaguchi, Takeshi Katsuda, Takafumi Ninomiya, Takashi Tokino, Takahiro Ochiya, Atsushi Miyajima, Toshihiro Mitaka |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/5ae34e70df8044cf9ed9cd6e6564d196 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
p-STAT3 is a PDC-E2 interacting partner in human cholangiocytes and hepatocytes with potential pathobiological implications
por: Ewa Kilanczyk, et al.
Publicado: (2021) -
Human extrahepatic and intrahepatic cholangiocyte organoids show region-specific differentiation potential and model cystic fibrosis-related bile duct disease
por: Monique M. A. Verstegen, et al.
Publicado: (2020) -
YAP determines the cell fate of injured mouse hepatocytes in vivo
por: Norio Miyamura, et al.
Publicado: (2017) -
Erratum: YAP determines the cell fate of injured mouse hepatocytes in vivo
por: Norio Miyamura, et al.
Publicado: (2017) -
Induction of differentiation of intrahepatic cholangiocarcinoma cells to functional hepatocytes using an organoid culture system
por: Yoshimasa Saito, et al.
Publicado: (2018)