Effect of letrozole on spermogram parameters and hormonal profile in infertile men: A clinical trial study
Objective. There is no reliable treatment for men with idiopathic infertility, but the relationship between severe sperm production and the ratio of estrogen to testosterone levels has been shown. Aromatase is an enzyme that plays an important role in converting testosterone to estradiol and androst...
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2019
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oai:doaj.org-article:5aea958522c1400ca03c5c7fc0b9de2b2021-12-02T16:40:25ZEffect of letrozole on spermogram parameters and hormonal profile in infertile men: A clinical trial study1336-032910.2478/enr-2019-0023https://doaj.org/article/5aea958522c1400ca03c5c7fc0b9de2b2019-10-01T00:00:00Zhttps://doi.org/10.2478/enr-2019-0023https://doaj.org/toc/1336-0329Objective. There is no reliable treatment for men with idiopathic infertility, but the relationship between severe sperm production and the ratio of estrogen to testosterone levels has been shown. Aromatase is an enzyme that plays an important role in converting testosterone to estradiol and androstenedione to estrogen. Aromatase inhibitors can increase testosterone and androgen production without increasing the amount of estrogen in circulation. The aim of this study was to evaluate the effect of aromatase inhibitor letrozole on the male infertility.Peivandi SepidehJafarpour HamedAbbaspour MinaEbadi AghdasSciendoarticlemale infertilityaromatase inhibitortestosteroneestradiolletrozoleDiseases of the endocrine glands. Clinical endocrinologyRC648-665ENEndocrine Regulations, Vol 53, Iss 4, Pp 231-236 (2019) |
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DOAJ |
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DOAJ |
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EN |
| topic |
male infertility aromatase inhibitor testosterone estradiol letrozole Diseases of the endocrine glands. Clinical endocrinology RC648-665 |
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male infertility aromatase inhibitor testosterone estradiol letrozole Diseases of the endocrine glands. Clinical endocrinology RC648-665 Peivandi Sepideh Jafarpour Hamed Abbaspour Mina Ebadi Aghdas Effect of letrozole on spermogram parameters and hormonal profile in infertile men: A clinical trial study |
| description |
Objective. There is no reliable treatment for men with idiopathic infertility, but the relationship between severe sperm production and the ratio of estrogen to testosterone levels has been shown. Aromatase is an enzyme that plays an important role in converting testosterone to estradiol and androstenedione to estrogen. Aromatase inhibitors can increase testosterone and androgen production without increasing the amount of estrogen in circulation. The aim of this study was to evaluate the effect of aromatase inhibitor letrozole on the male infertility. |
| format |
article |
| author |
Peivandi Sepideh Jafarpour Hamed Abbaspour Mina Ebadi Aghdas |
| author_facet |
Peivandi Sepideh Jafarpour Hamed Abbaspour Mina Ebadi Aghdas |
| author_sort |
Peivandi Sepideh |
| title |
Effect of letrozole on spermogram parameters and hormonal profile in infertile men: A clinical trial study |
| title_short |
Effect of letrozole on spermogram parameters and hormonal profile in infertile men: A clinical trial study |
| title_full |
Effect of letrozole on spermogram parameters and hormonal profile in infertile men: A clinical trial study |
| title_fullStr |
Effect of letrozole on spermogram parameters and hormonal profile in infertile men: A clinical trial study |
| title_full_unstemmed |
Effect of letrozole on spermogram parameters and hormonal profile in infertile men: A clinical trial study |
| title_sort |
effect of letrozole on spermogram parameters and hormonal profile in infertile men: a clinical trial study |
| publisher |
Sciendo |
| publishDate |
2019 |
| url |
https://doaj.org/article/5aea958522c1400ca03c5c7fc0b9de2b |
| work_keys_str_mv |
AT peivandisepideh effectofletrozoleonspermogramparametersandhormonalprofileininfertilemenaclinicaltrialstudy AT jafarpourhamed effectofletrozoleonspermogramparametersandhormonalprofileininfertilemenaclinicaltrialstudy AT abbaspourmina effectofletrozoleonspermogramparametersandhormonalprofileininfertilemenaclinicaltrialstudy AT ebadiaghdas effectofletrozoleonspermogramparametersandhormonalprofileininfertilemenaclinicaltrialstudy |
| _version_ |
1718383574421340160 |