AIF and Scythe (Bat3) regulate phosphatidylserine exposure and macrophage clearance of cells undergoing Fas (APO-1)-mediated apoptosis.
Phosphatidylserine (PS) exposure on the cell surface has been considered a characteristic feature of apoptosis and serves as a molecular cue for engulfment of dying cells by phagocytes. However, the mechanism of PS exposure is still not fully elucidated. Here we show that the cytosolic release from...
Guardado en:
Autores principales: | Giulio Preta, Bengt Fadeel |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
|
Materias: | |
Acceso en línea: | https://doaj.org/article/5af07e3ca98b4524bf11f15f143aaa63 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
D4F alleviates macrophage-derived foam cell apoptosis by inhibiting the NF-κB-dependent Fas/FasL pathway
por: Hua Tian, et al.
Publicado: (2017) -
Phosphatidylserine-mediated platelet clearance by endothelium decreases platelet aggregates and procoagulant activity in sepsis
por: Ruishuang Ma, et al.
Publicado: (2017) -
RvD1 accelerates the resolution of inflammation by promoting apoptosis of the recruited macrophages via the ALX/FasL-FasR/caspase-3 signaling pathway
por: Shu-yang Xiang, et al.
Publicado: (2021) -
ZINC DEFICIENCY INDUCES FAS-MEDIATED APOPTOSIS
por: L. M. Karzakova
Publicado: (2014) -
Dysferlin-mediated phosphatidylserine sorting engages macrophages in sarcolemma repair
por: Volker Middel, et al.
Publicado: (2016)