Selective Upregulation of Transcripts for Six Molecules Related to T Cell Costimulation and Phagocyte Recruitment and Activation among 734 Immunity-Related Genes in the Brain during Perforin-Dependent, CD8<sup>+</sup> T Cell-Mediated Elimination of <named-content content-type="genus-species">Toxoplasma gondii</named-content> Cysts

Selective Upregulation of Transcripts for Six Molecules Related to T Cell Costimulation and Phagocyte Recruitment and Activation among 734 Immunity-Related Genes in the Brain during Perforin-Dependent, CD8<sup>+</sup> T Cell-Mediated Elimination of <named-content content-type="genus-species">Toxoplasma gondii</named-content> Cysts

ABSTRACT We recently found that an invasion of CD8+ cytotoxic T cells into tissue cysts of Toxoplasma gondii initiates an elimination of the cysts in association with an accumulation of microglia and macrophages. In the present study, we compared mRNA levels for 734 immune-related genes in the brain...

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Auteurs principaux: Jenny Lutshumba, Eri Ochiai, Qila Sa, Namrata Anand, Yasuhiro Suzuki
Format: article
Langue:EN
Publié: American Society for Microbiology 2020
Sujets:
CD8+ cytotoxic T cells
perforin
T cell invasion
coactivation molecules
phagocytes
chemokine receptor
Microbiology
QR1-502
Accès en ligne:https://doaj.org/article/5af1943053d94cc8b9948c7b6952f33a
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