MRFalign: protein homology detection through alignment of Markov random fields.

Sequence-based protein homology detection has been extensively studied and so far the most sensitive method is based upon comparison of protein sequence profiles, which are derived from multiple sequence alignment (MSA) of sequence homologs in a protein family. A sequence profile is usually represen...

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Autores principales: Jianzhu Ma, Sheng Wang, Zhiyong Wang, Jinbo Xu
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/5af7307a47024e8695343ecfb15b8e60
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