A synthetic RNA editing factor edits its target site in chloroplasts and bacteria

RNA editing in plants is carried out by pentatricopeptide repeat (PPR) proteins. Royan et al construct an editing factor from synthetic PPR motifs and show that it can be expressed in plants and bacteria and edits the chosen target RNA with high specificity, demonstrating the potential of PPR protei...

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Autores principales:	Santana Royan, Bernard Gutmann, Catherine Colas des Francs-Small, Suvi Honkanen, Jason Schmidberger, Ashley Soet, Yueming Kelly Sun, Lilian Vincis Pereira Sanglard, Charles S. Bond, Ian Small
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/5afcd032293b42959b20d28c99d0cfce
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spelling	oai:doaj.org-article:5afcd032293b42959b20d28c99d0cfce2021-12-02T14:35:52ZA synthetic RNA editing factor edits its target site in chloroplasts and bacteria10.1038/s42003-021-02062-92399-3642https://doaj.org/article/5afcd032293b42959b20d28c99d0cfce2021-05-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02062-9https://doaj.org/toc/2399-3642RNA editing in plants is carried out by pentatricopeptide repeat (PPR) proteins. Royan et al construct an editing factor from synthetic PPR motifs and show that it can be expressed in plants and bacteria and edits the chosen target RNA with high specificity, demonstrating the potential of PPR proteins as programmable RNA editing factors.Santana RoyanBernard GutmannCatherine Colas des Francs-SmallSuvi HonkanenJason SchmidbergerAshley SoetYueming Kelly SunLilian Vincis Pereira SanglardCharles S. BondIan SmallNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Santana Royan Bernard Gutmann Catherine Colas des Francs-Small Suvi Honkanen Jason Schmidberger Ashley Soet Yueming Kelly Sun Lilian Vincis Pereira Sanglard Charles S. Bond Ian Small A synthetic RNA editing factor edits its target site in chloroplasts and bacteria
description	RNA editing in plants is carried out by pentatricopeptide repeat (PPR) proteins. Royan et al construct an editing factor from synthetic PPR motifs and show that it can be expressed in plants and bacteria and edits the chosen target RNA with high specificity, demonstrating the potential of PPR proteins as programmable RNA editing factors.
format	article
author	Santana Royan Bernard Gutmann Catherine Colas des Francs-Small Suvi Honkanen Jason Schmidberger Ashley Soet Yueming Kelly Sun Lilian Vincis Pereira Sanglard Charles S. Bond Ian Small
author_facet	Santana Royan Bernard Gutmann Catherine Colas des Francs-Small Suvi Honkanen Jason Schmidberger Ashley Soet Yueming Kelly Sun Lilian Vincis Pereira Sanglard Charles S. Bond Ian Small
author_sort	Santana Royan
title	A synthetic RNA editing factor edits its target site in chloroplasts and bacteria
title_short	A synthetic RNA editing factor edits its target site in chloroplasts and bacteria
title_full	A synthetic RNA editing factor edits its target site in chloroplasts and bacteria
title_fullStr	A synthetic RNA editing factor edits its target site in chloroplasts and bacteria
title_full_unstemmed	A synthetic RNA editing factor edits its target site in chloroplasts and bacteria
title_sort	synthetic rna editing factor edits its target site in chloroplasts and bacteria
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/5afcd032293b42959b20d28c99d0cfce
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A synthetic RNA editing factor edits its target site in chloroplasts and bacteria

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