Dengue virus-reactive CD8+ T cells mediate cross-protection against subsequent Zika virus challenge
Dengue virus-specific antibody and CD8+ T cells that cross-react with Zika virus have been described. Here, the authors establish a functionally protective role for cross-reactive dengue virus-specific CD8+ T cells during challenge with Zika virus.
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Nature Portfolio
2017
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oai:doaj.org-article:5afda4a06f2a4cd69385bda4898e17172021-12-02T15:38:40ZDengue virus-reactive CD8+ T cells mediate cross-protection against subsequent Zika virus challenge10.1038/s41467-017-01669-z2041-1723https://doaj.org/article/5afda4a06f2a4cd69385bda4898e17172017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01669-zhttps://doaj.org/toc/2041-1723Dengue virus-specific antibody and CD8+ T cells that cross-react with Zika virus have been described. Here, the authors establish a functionally protective role for cross-reactive dengue virus-specific CD8+ T cells during challenge with Zika virus.Jinsheng WenAnnie Elong NgonoJose Angel Regla-NavaKenneth KimMatthew J. GormanMichael S. DiamondSujan ShrestaNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Jinsheng Wen Annie Elong Ngono Jose Angel Regla-Nava Kenneth Kim Matthew J. Gorman Michael S. Diamond Sujan Shresta Dengue virus-reactive CD8+ T cells mediate cross-protection against subsequent Zika virus challenge |
description |
Dengue virus-specific antibody and CD8+ T cells that cross-react with Zika virus have been described. Here, the authors establish a functionally protective role for cross-reactive dengue virus-specific CD8+ T cells during challenge with Zika virus. |
format |
article |
author |
Jinsheng Wen Annie Elong Ngono Jose Angel Regla-Nava Kenneth Kim Matthew J. Gorman Michael S. Diamond Sujan Shresta |
author_facet |
Jinsheng Wen Annie Elong Ngono Jose Angel Regla-Nava Kenneth Kim Matthew J. Gorman Michael S. Diamond Sujan Shresta |
author_sort |
Jinsheng Wen |
title |
Dengue virus-reactive CD8+ T cells mediate cross-protection against subsequent Zika virus challenge |
title_short |
Dengue virus-reactive CD8+ T cells mediate cross-protection against subsequent Zika virus challenge |
title_full |
Dengue virus-reactive CD8+ T cells mediate cross-protection against subsequent Zika virus challenge |
title_fullStr |
Dengue virus-reactive CD8+ T cells mediate cross-protection against subsequent Zika virus challenge |
title_full_unstemmed |
Dengue virus-reactive CD8+ T cells mediate cross-protection against subsequent Zika virus challenge |
title_sort |
dengue virus-reactive cd8+ t cells mediate cross-protection against subsequent zika virus challenge |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/5afda4a06f2a4cd69385bda4898e1717 |
work_keys_str_mv |
AT jinshengwen denguevirusreactivecd8tcellsmediatecrossprotectionagainstsubsequentzikaviruschallenge AT annieelongngono denguevirusreactivecd8tcellsmediatecrossprotectionagainstsubsequentzikaviruschallenge AT joseangelreglanava denguevirusreactivecd8tcellsmediatecrossprotectionagainstsubsequentzikaviruschallenge AT kennethkim denguevirusreactivecd8tcellsmediatecrossprotectionagainstsubsequentzikaviruschallenge AT matthewjgorman denguevirusreactivecd8tcellsmediatecrossprotectionagainstsubsequentzikaviruschallenge AT michaelsdiamond denguevirusreactivecd8tcellsmediatecrossprotectionagainstsubsequentzikaviruschallenge AT sujanshresta denguevirusreactivecd8tcellsmediatecrossprotectionagainstsubsequentzikaviruschallenge |
_version_ |
1718386111297880064 |