Xmrk, kras and myc transgenic zebrafish liver cancer models share molecular signatures with subsets of human hepatocellular carcinoma.

Previously three oncogene transgenic zebrafish lines with inducible expression of xmrk, kras or Myc in the liver have been generated and these transgenic lines develop oncogene-addicted liver tumors upon chemical induction. In the current study, comparative transcriptomic approaches were used to exa...

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Auteurs principaux: Weiling Zheng, Zhen Li, Anh Tuan Nguyen, Caixia Li, Alexander Emelyanov, Zhiyuan Gong
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
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Accès en ligne:https://doaj.org/article/5aff7fea2a84455ebd86a7664a5e460e
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