Cyclophilin E functions as a negative regulator to influenza virus replication by impairing the formation of the viral ribonucleoprotein complex.

Cyclophilin E functions as a negative regulator to influenza virus replication by impairing the formation of the viral ribonucleoprotein complex.

<h4>Background</h4>The nucleoprotein (NP) of influenza A virus is a multifunctional protein that plays a critical role in the replication and transcription of the viral genome. Therefore, examining host factors that interact with NP may shed light on the mechanism of host restriction bar...

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Autores principales: Zengfu Wang, Xiaoling Liu, Zhendong Zhao, Chongfeng Xu, Ke Zhang, Caiwei Chen, Lei Sun, George F Gao, Xin Ye, Wenjun Liu
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/5b052dc924e54ad580b675f6edbe0ffe
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