Role of Bacterial Flora in Oral Cancer- An Insight

The human body contains about 1014 bacteria which usually colonise different parts of the body. The bacterial flora is important for a person’s health as well as normal functioning of tissue and organ systems. Bacteria are single celled organisms and are found on almost all surfaces of human body....

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Autores principales:	R Ananthalakshmi, M Priya, Nadeem Jeddy, LJ Sailakshmi
Formato:	article
Lenguaje:	EN
Publicado:	JCDR Research and Publications Private Limited 2021
Materias:	carcinogens chronic inflammation literature review mucous membrane oral carcinogenesis Medicine R
Acceso en línea:	https://doaj.org/article/5b129e1c7359428280b42061ae34023f
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spelling	oai:doaj.org-article:5b129e1c7359428280b42061ae34023f2021-11-14T07:00:16ZRole of Bacterial Flora in Oral Cancer- An Insight10.7860/JCDR/2021/48929.154132249-782X0973-709Xhttps://doaj.org/article/5b129e1c7359428280b42061ae34023f2021-09-01T00:00:00Zhttps://www.jcdr.net/articles/PDF/15413/48929_CE[Ra1]_F[SK]_PF1(SG_SHU)_PFA(SG_KM)_PN(KM).pdfhttps://doaj.org/toc/2249-782Xhttps://doaj.org/toc/0973-709XThe human body contains about 1014 bacteria which usually colonise different parts of the body. The bacterial flora is important for a person’s health as well as normal functioning of tissue and organ systems. Bacteria are single celled organisms and are found on almost all surfaces of human body. They act in synergy with host immune mechanism and provide protection against various undesirable foreign invasions, especially in the oral cavity, where they exist in a diversified form which survive in a symbiotic relationship with the host. When there is a disturbance in this equilibrium due to various factors like trauma or tobacco smoking, betel nut chewing and alcohol intake, which makes the mucous membrane more permeable to invading microorganisms, these commensal bacterial species can become virulent and give rise to oral diseases ranging from dental caries to oral carcinoma. The effects of these bacteria can be either direct or indirect initiation of chronic inflammation, formation of procarcinogens that contribute to the development of oral carcinoma. This article focuses on the role of oral bacterial flora in initiation and progression of oral carcinogenesis. Various bacterial and fungal species associated with oral carcinoma and predominant bacterial species in oral cavity and oropharyngeal region along with measures to prevent their adverse effects are described.R AnanthalakshmiM PriyaNadeem JeddyLJ SailakshmiJCDR Research and Publications Private Limitedarticlecarcinogenschronic inflammationliterature reviewmucous membraneoral carcinogenesisMedicineRENJournal of Clinical and Diagnostic Research, Vol 15, Iss 9, Pp ZE23-ZE27 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	carcinogens chronic inflammation literature review mucous membrane oral carcinogenesis Medicine R
spellingShingle	carcinogens chronic inflammation literature review mucous membrane oral carcinogenesis Medicine R R Ananthalakshmi M Priya Nadeem Jeddy LJ Sailakshmi Role of Bacterial Flora in Oral Cancer- An Insight
description	The human body contains about 1014 bacteria which usually colonise different parts of the body. The bacterial flora is important for a person’s health as well as normal functioning of tissue and organ systems. Bacteria are single celled organisms and are found on almost all surfaces of human body. They act in synergy with host immune mechanism and provide protection against various undesirable foreign invasions, especially in the oral cavity, where they exist in a diversified form which survive in a symbiotic relationship with the host. When there is a disturbance in this equilibrium due to various factors like trauma or tobacco smoking, betel nut chewing and alcohol intake, which makes the mucous membrane more permeable to invading microorganisms, these commensal bacterial species can become virulent and give rise to oral diseases ranging from dental caries to oral carcinoma. The effects of these bacteria can be either direct or indirect initiation of chronic inflammation, formation of procarcinogens that contribute to the development of oral carcinoma. This article focuses on the role of oral bacterial flora in initiation and progression of oral carcinogenesis. Various bacterial and fungal species associated with oral carcinoma and predominant bacterial species in oral cavity and oropharyngeal region along with measures to prevent their adverse effects are described.
format	article
author	R Ananthalakshmi M Priya Nadeem Jeddy LJ Sailakshmi
author_facet	R Ananthalakshmi M Priya Nadeem Jeddy LJ Sailakshmi
author_sort	R Ananthalakshmi
title	Role of Bacterial Flora in Oral Cancer- An Insight
title_short	Role of Bacterial Flora in Oral Cancer- An Insight
title_full	Role of Bacterial Flora in Oral Cancer- An Insight
title_fullStr	Role of Bacterial Flora in Oral Cancer- An Insight
title_full_unstemmed	Role of Bacterial Flora in Oral Cancer- An Insight
title_sort	role of bacterial flora in oral cancer- an insight
publisher	JCDR Research and Publications Private Limited
publishDate	2021
url	https://doaj.org/article/5b129e1c7359428280b42061ae34023f
work_keys_str_mv	AT rananthalakshmi roleofbacterialflorainoralcanceraninsight AT mpriya roleofbacterialflorainoralcanceraninsight AT nadeemjeddy roleofbacterialflorainoralcanceraninsight AT ljsailakshmi roleofbacterialflorainoralcanceraninsight
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Role of Bacterial Flora in Oral Cancer- An Insight

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