Reviving the Weizmann process for commercial n-butanol production

Organic solvent n-butanol is produced mainly by petrochemical method. Here, the authors revive the historical Weizmann process by engineering Clostridium acetobutylicum strain and developing low pressure distillation and high cell density cultures for n-butanol continuous production at high-yield ti...

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Autores principales: Ngoc-Phuong-Thao Nguyen, Céline Raynaud, Isabelle Meynial-Salles, Philippe Soucaille
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/5b14181a69f147c6ad1418b84cbf335f
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Sumario:Organic solvent n-butanol is produced mainly by petrochemical method. Here, the authors revive the historical Weizmann process by engineering Clostridium acetobutylicum strain and developing low pressure distillation and high cell density cultures for n-butanol continuous production at high-yield titer and productivity.