Effects of intravitreal injection of siRNA against caspase-2 on retinal and optic nerve degeneration in air blast induced ocular trauma

Abstract Ocular repeated air blast injuries occur from low overpressure blast wave exposure, which are often repeated and in quick succession. We have shown that caspase-2 caused the death of retinal ganglion cells (RGC) after blunt ocular trauma. Here, we investigated if caspase-2 also mediates RGC...

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Autores principales: Chloe N. Thomas, Alexandra Bernardo-Colón, Ella Courtie, Gareth Essex, Tonia S. Rex, Richard J. Blanch, Zubair Ahmed
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/5b1afdd3ed344166bd25ff7af7659085
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