Transcription coordinates histone amounts and genome content
Accurate regulation of protein concentrations according to changes in cell volume that accompany growth and changes in biosynthetic capacity is an important component of cellular homeostasis. Here, using the model organism S. cerevisiae, the authors show how histone production is quantitatively coup...
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Nature Portfolio
2021
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oai:doaj.org-article:5b228a49de404295a27fdb7a29d0d3e82021-12-02T15:39:43ZTranscription coordinates histone amounts and genome content10.1038/s41467-021-24451-82041-1723https://doaj.org/article/5b228a49de404295a27fdb7a29d0d3e82021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24451-8https://doaj.org/toc/2041-1723Accurate regulation of protein concentrations according to changes in cell volume that accompany growth and changes in biosynthetic capacity is an important component of cellular homeostasis. Here, using the model organism S. cerevisiae, the authors show how histone production is quantitatively coupled to genome content through the intrinsic properties of histone promoters.Kora-Lee ClaudeDaniela BureikDimitra ChatzitheodoridouPetia AdarskaAbhyudai SinghKurt M. SchmollerNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-17 (2021) |
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Science Q Kora-Lee Claude Daniela Bureik Dimitra Chatzitheodoridou Petia Adarska Abhyudai Singh Kurt M. Schmoller Transcription coordinates histone amounts and genome content |
description |
Accurate regulation of protein concentrations according to changes in cell volume that accompany growth and changes in biosynthetic capacity is an important component of cellular homeostasis. Here, using the model organism S. cerevisiae, the authors show how histone production is quantitatively coupled to genome content through the intrinsic properties of histone promoters. |
format |
article |
author |
Kora-Lee Claude Daniela Bureik Dimitra Chatzitheodoridou Petia Adarska Abhyudai Singh Kurt M. Schmoller |
author_facet |
Kora-Lee Claude Daniela Bureik Dimitra Chatzitheodoridou Petia Adarska Abhyudai Singh Kurt M. Schmoller |
author_sort |
Kora-Lee Claude |
title |
Transcription coordinates histone amounts and genome content |
title_short |
Transcription coordinates histone amounts and genome content |
title_full |
Transcription coordinates histone amounts and genome content |
title_fullStr |
Transcription coordinates histone amounts and genome content |
title_full_unstemmed |
Transcription coordinates histone amounts and genome content |
title_sort |
transcription coordinates histone amounts and genome content |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/5b228a49de404295a27fdb7a29d0d3e8 |
work_keys_str_mv |
AT koraleeclaude transcriptioncoordinateshistoneamountsandgenomecontent AT danielabureik transcriptioncoordinateshistoneamountsandgenomecontent AT dimitrachatzitheodoridou transcriptioncoordinateshistoneamountsandgenomecontent AT petiaadarska transcriptioncoordinateshistoneamountsandgenomecontent AT abhyudaisingh transcriptioncoordinateshistoneamountsandgenomecontent AT kurtmschmoller transcriptioncoordinateshistoneamountsandgenomecontent |
_version_ |
1718385873624498176 |