Transcription coordinates histone amounts and genome content

Accurate regulation of protein concentrations according to changes in cell volume that accompany growth and changes in biosynthetic capacity is an important component of cellular homeostasis. Here, using the model organism S. cerevisiae, the authors show how histone production is quantitatively coup...

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Autores principales: Kora-Lee Claude, Daniela Bureik, Dimitra Chatzitheodoridou, Petia Adarska, Abhyudai Singh, Kurt M. Schmoller
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/5b228a49de404295a27fdb7a29d0d3e8
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spelling oai:doaj.org-article:5b228a49de404295a27fdb7a29d0d3e82021-12-02T15:39:43ZTranscription coordinates histone amounts and genome content10.1038/s41467-021-24451-82041-1723https://doaj.org/article/5b228a49de404295a27fdb7a29d0d3e82021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24451-8https://doaj.org/toc/2041-1723Accurate regulation of protein concentrations according to changes in cell volume that accompany growth and changes in biosynthetic capacity is an important component of cellular homeostasis. Here, using the model organism S. cerevisiae, the authors show how histone production is quantitatively coupled to genome content through the intrinsic properties of histone promoters.Kora-Lee ClaudeDaniela BureikDimitra ChatzitheodoridouPetia AdarskaAbhyudai SinghKurt M. SchmollerNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Kora-Lee Claude
Daniela Bureik
Dimitra Chatzitheodoridou
Petia Adarska
Abhyudai Singh
Kurt M. Schmoller
Transcription coordinates histone amounts and genome content
description Accurate regulation of protein concentrations according to changes in cell volume that accompany growth and changes in biosynthetic capacity is an important component of cellular homeostasis. Here, using the model organism S. cerevisiae, the authors show how histone production is quantitatively coupled to genome content through the intrinsic properties of histone promoters.
format article
author Kora-Lee Claude
Daniela Bureik
Dimitra Chatzitheodoridou
Petia Adarska
Abhyudai Singh
Kurt M. Schmoller
author_facet Kora-Lee Claude
Daniela Bureik
Dimitra Chatzitheodoridou
Petia Adarska
Abhyudai Singh
Kurt M. Schmoller
author_sort Kora-Lee Claude
title Transcription coordinates histone amounts and genome content
title_short Transcription coordinates histone amounts and genome content
title_full Transcription coordinates histone amounts and genome content
title_fullStr Transcription coordinates histone amounts and genome content
title_full_unstemmed Transcription coordinates histone amounts and genome content
title_sort transcription coordinates histone amounts and genome content
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/5b228a49de404295a27fdb7a29d0d3e8
work_keys_str_mv AT koraleeclaude transcriptioncoordinateshistoneamountsandgenomecontent
AT danielabureik transcriptioncoordinateshistoneamountsandgenomecontent
AT dimitrachatzitheodoridou transcriptioncoordinateshistoneamountsandgenomecontent
AT petiaadarska transcriptioncoordinateshistoneamountsandgenomecontent
AT abhyudaisingh transcriptioncoordinateshistoneamountsandgenomecontent
AT kurtmschmoller transcriptioncoordinateshistoneamountsandgenomecontent
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