Ploidy and recombination proficiency shape the evolutionary adaptation to constitutive DNA replication stress
In haploid budding yeast, evolutionary adaptation to constitutive DNA replication stress alters three genome maintenance modules: DNA replication, the DNA damage checkpoint, and sister chromatid cohesion. We asked how these trajectories depend on genomic features by comparing the adaptation in three...
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Main Authors: | Marco Fumasoni, Andrew W. Murray |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2021
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Online Access: | https://doaj.org/article/5b2d4bd9754149f6b69d814af7325e3e |
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