Peroxisomal targeting of a protein phosphatase type 2C via mitochondrial transit

Import of proteins into specific cellular compartments is critical for organelle function and several proteins are known to be imported into multiple compartments. Here, the authors report that the protein Ptc5 is first sorted to and processed in the mitochondria before being targeted to peroxisomes...

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Autores principales: Thorsten Stehlik, Marco Kremp, Jörg Kahnt, Michael Bölker, Johannes Freitag
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/5b3a9bdf8023491aa56956b14e0bd050
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Sumario:Import of proteins into specific cellular compartments is critical for organelle function and several proteins are known to be imported into multiple compartments. Here, the authors report that the protein Ptc5 is first sorted to and processed in the mitochondria before being targeted to peroxisomes, which may influence mitochondria-peroxisome interorganellar contact.