$Cardiopulmonary bypass does not consequentially contribute to postoperative distant metastasis of giant refractory thoracic tumors: A retrospective study with long‐term follow‐up$
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Cardiopulmonary bypass does not consequentially contribute to postoperative distant metastasis of giant refractory thoracic tumors: A retrospective study with long‐term follow‐up

Abstract Background Few clinical research studies with long‐term follow‐up have revealed whether cardiopulmonary bypass (CPB) increases the risk of postoperative distant metastasis in patients with giant refractory thoracic tumors. The present study evaluated the risk of distant metastasis after sur...

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Autores principales:	Lei Chen, Xuejuan Zhu, Rongying Zhu, Xing Jin, Liping Tan, Yongbing Chen
Formato:	article
Lenguaje:	EN
Publicado:	Wiley 2021
Materias:	cardiopulmonary bypass distant metastasis giant refractory thoracic tumors recurrence Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/5b425cf1f48d4e4aac201870ec858150
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spelling	oai:doaj.org-article:5b425cf1f48d4e4aac201870ec8581502021-11-14T23:28:25ZCardiopulmonary bypass does not consequentially contribute to postoperative distant metastasis of giant refractory thoracic tumors: A retrospective study with long‐term follow‐up1759-77141759-770610.1111/1759-7714.14162https://doaj.org/article/5b425cf1f48d4e4aac201870ec8581502021-11-01T00:00:00Zhttps://doi.org/10.1111/1759-7714.14162https://doaj.org/toc/1759-7706https://doaj.org/toc/1759-7714Abstract Background Few clinical research studies with long‐term follow‐up have revealed whether cardiopulmonary bypass (CPB) increases the risk of postoperative distant metastasis in patients with giant refractory thoracic tumors. The present study evaluated the risk of distant metastasis after surgery utilizing CPB with long‐term follow‐up. Methods Clinical data for patients with giant refractory thoracic tumors who underwent resection with the use of CPB in the Second Affiliated Hospital of Soochow University during the past 11 years were retrospectively reviewed. Results Of the 14 patients with giant refractory thoracic tumors who had undergone surgery under CPB, 10 patients (71.4%) were completely resected. Twelve patients were followed up for 13–127 months with 10 patients were completely resected and two patients could not be completely resected due to severe tissue invasion. Three patients (25%) suffered from distant metastasis, and four patients (33.3%) experienced local recurrence. Only one patient (1/10) with complete resection suffered from distant metastasis, while two patients (2/10) experienced local recurrence. Two patients (2/2) with major resection suffered from both distant metastasis and local recurrence. Median overall survival for patients who have been regularly followed up was 50 months with 1‐, 5‐, and 10‐year survival of 100%, 75%, and 66.7%. No difference was found between the distant metastasis survival and the local recurrence survival. (p = 0.99). Conclusions CPB is an effective strategy for complete resection of the giant refractory thoracic tumors with an acceptable risk of postoperative distant metastasis for some patients.Lei ChenXuejuan ZhuRongying ZhuXing JinLiping TanYongbing ChenWileyarticlecardiopulmonary bypassdistant metastasisgiant refractory thoracic tumorsrecurrenceNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENThoracic Cancer, Vol 12, Iss 22, Pp 2990-2995 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	cardiopulmonary bypass distant metastasis giant refractory thoracic tumors recurrence Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	cardiopulmonary bypass distant metastasis giant refractory thoracic tumors recurrence Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Lei Chen Xuejuan Zhu Rongying Zhu Xing Jin Liping Tan Yongbing Chen Cardiopulmonary bypass does not consequentially contribute to postoperative distant metastasis of giant refractory thoracic tumors: A retrospective study with long‐term follow‐up
description	Abstract Background Few clinical research studies with long‐term follow‐up have revealed whether cardiopulmonary bypass (CPB) increases the risk of postoperative distant metastasis in patients with giant refractory thoracic tumors. The present study evaluated the risk of distant metastasis after surgery utilizing CPB with long‐term follow‐up. Methods Clinical data for patients with giant refractory thoracic tumors who underwent resection with the use of CPB in the Second Affiliated Hospital of Soochow University during the past 11 years were retrospectively reviewed. Results Of the 14 patients with giant refractory thoracic tumors who had undergone surgery under CPB, 10 patients (71.4%) were completely resected. Twelve patients were followed up for 13–127 months with 10 patients were completely resected and two patients could not be completely resected due to severe tissue invasion. Three patients (25%) suffered from distant metastasis, and four patients (33.3%) experienced local recurrence. Only one patient (1/10) with complete resection suffered from distant metastasis, while two patients (2/10) experienced local recurrence. Two patients (2/2) with major resection suffered from both distant metastasis and local recurrence. Median overall survival for patients who have been regularly followed up was 50 months with 1‐, 5‐, and 10‐year survival of 100%, 75%, and 66.7%. No difference was found between the distant metastasis survival and the local recurrence survival. (p = 0.99). Conclusions CPB is an effective strategy for complete resection of the giant refractory thoracic tumors with an acceptable risk of postoperative distant metastasis for some patients.
format	article
author	Lei Chen Xuejuan Zhu Rongying Zhu Xing Jin Liping Tan Yongbing Chen
author_facet	Lei Chen Xuejuan Zhu Rongying Zhu Xing Jin Liping Tan Yongbing Chen
author_sort	Lei Chen
title	Cardiopulmonary bypass does not consequentially contribute to postoperative distant metastasis of giant refractory thoracic tumors: A retrospective study with long‐term follow‐up
title_short	Cardiopulmonary bypass does not consequentially contribute to postoperative distant metastasis of giant refractory thoracic tumors: A retrospective study with long‐term follow‐up
title_full	Cardiopulmonary bypass does not consequentially contribute to postoperative distant metastasis of giant refractory thoracic tumors: A retrospective study with long‐term follow‐up
title_fullStr	Cardiopulmonary bypass does not consequentially contribute to postoperative distant metastasis of giant refractory thoracic tumors: A retrospective study with long‐term follow‐up
title_full_unstemmed	Cardiopulmonary bypass does not consequentially contribute to postoperative distant metastasis of giant refractory thoracic tumors: A retrospective study with long‐term follow‐up
title_sort	cardiopulmonary bypass does not consequentially contribute to postoperative distant metastasis of giant refractory thoracic tumors: a retrospective study with long‐term follow‐up
publisher	Wiley
publishDate	2021
url	https://doaj.org/article/5b425cf1f48d4e4aac201870ec858150
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Cardiopulmonary bypass does not consequentially contribute to postoperative distant metastasis of giant refractory thoracic tumors: A retrospective study with long‐term follow‐up

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