Contribution of Lipid Oxidation and Ferroptosis to Radiotherapy Efficacy
Radiotherapy promotes tumor cell death and senescence through the induction of oxidative damage. Recent work has highlighted the importance of lipid peroxidation for radiotherapy efficacy. Excessive lipid peroxidation can promote ferroptosis, a regulated form of cell death. In this review, we addres...
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Main Authors: | Ashley N. Pearson, Joseph Carmicheal, Long Jiang, Yu Leo Lei, Michael D. Green |
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Format: | article |
Language: | EN |
Published: |
MDPI AG
2021
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Online Access: | https://doaj.org/article/5b4a7ed5e11a4465a7602a24eee38ea1 |
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