Factors influencing self-selected walking speed in fibrotic interstitial lung disease

Abstract This study aimed to investigate the walking economy and possible factors influencing self-selected walking speed (SSWS) in patients with fibrotic interstitial lung disease (ILD) compared to controls. In this study, 10 patients with ILD (mean age: 63.8 ± 9.2 years, forced expiratory volume i...

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Autores principales:	Gabriela Fischer, Francisco B. de Queiroz, Danilo C. Berton, Pedro Schons, Henrique B. Oliveira, Marcelo Coertjens, Mathieu Gruet, Leonardo A. Peyré-Tartaruga
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/5b4fd7023186499ba57f41c4d33917be
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spelling	oai:doaj.org-article:5b4fd7023186499ba57f41c4d33917be2021-12-02T17:39:49ZFactors influencing self-selected walking speed in fibrotic interstitial lung disease10.1038/s41598-021-91734-x2045-2322https://doaj.org/article/5b4fd7023186499ba57f41c4d33917be2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-91734-xhttps://doaj.org/toc/2045-2322Abstract This study aimed to investigate the walking economy and possible factors influencing self-selected walking speed (SSWS) in patients with fibrotic interstitial lung disease (ILD) compared to controls. In this study, 10 patients with ILD (mean age: 63.8 ± 9.2 years, forced expiratory volume in the first second: 56 ± 7% of predicted) and 10 healthy controls underwent resting pulmonary function tests, cardiopulmonary exercise, and submaximal treadmill walking tests at different speeds. The walking economy was assessed by calculating the cost-of-transport (CoT). Dynamic stability was assessed by stride-to-stride fluctuations using video recordings. Patients with ILD showed reduced peak oxygen uptake with a tachypneic breathing pattern and significant oxygen desaturation during exercise. The CoT did not differ between the groups (p = 0.680), but dyspnea and SpO2 were higher and lower, respectively, in patients with ILD at the same relative speeds. SSWS was reduced in ILD patients (2.6 ± 0.9 vs. 4.2 ± 0.4 km h−1 p = 0.001) and did not correspond to the energetically optimal walking speed. Dynamic stability was significantly lower in patients with ILD than in healthy controls, mainly at lower speeds. Patients with ILD presented a similar cost of transport compared to healthy controls; however, they chose lower SSWS despite higher walking energy expenditure. Although walking stability and dyspnea were negatively affected, these factors were not associated with the slower walking speed chosen by individuals with ILD.Gabriela FischerFrancisco B. de QueirozDanilo C. BertonPedro SchonsHenrique B. OliveiraMarcelo CoertjensMathieu GruetLeonardo A. Peyré-TartarugaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Gabriela Fischer Francisco B. de Queiroz Danilo C. Berton Pedro Schons Henrique B. Oliveira Marcelo Coertjens Mathieu Gruet Leonardo A. Peyré-Tartaruga Factors influencing self-selected walking speed in fibrotic interstitial lung disease
description	Abstract This study aimed to investigate the walking economy and possible factors influencing self-selected walking speed (SSWS) in patients with fibrotic interstitial lung disease (ILD) compared to controls. In this study, 10 patients with ILD (mean age: 63.8 ± 9.2 years, forced expiratory volume in the first second: 56 ± 7% of predicted) and 10 healthy controls underwent resting pulmonary function tests, cardiopulmonary exercise, and submaximal treadmill walking tests at different speeds. The walking economy was assessed by calculating the cost-of-transport (CoT). Dynamic stability was assessed by stride-to-stride fluctuations using video recordings. Patients with ILD showed reduced peak oxygen uptake with a tachypneic breathing pattern and significant oxygen desaturation during exercise. The CoT did not differ between the groups (p = 0.680), but dyspnea and SpO2 were higher and lower, respectively, in patients with ILD at the same relative speeds. SSWS was reduced in ILD patients (2.6 ± 0.9 vs. 4.2 ± 0.4 km h−1 p = 0.001) and did not correspond to the energetically optimal walking speed. Dynamic stability was significantly lower in patients with ILD than in healthy controls, mainly at lower speeds. Patients with ILD presented a similar cost of transport compared to healthy controls; however, they chose lower SSWS despite higher walking energy expenditure. Although walking stability and dyspnea were negatively affected, these factors were not associated with the slower walking speed chosen by individuals with ILD.
format	article
author	Gabriela Fischer Francisco B. de Queiroz Danilo C. Berton Pedro Schons Henrique B. Oliveira Marcelo Coertjens Mathieu Gruet Leonardo A. Peyré-Tartaruga
author_facet	Gabriela Fischer Francisco B. de Queiroz Danilo C. Berton Pedro Schons Henrique B. Oliveira Marcelo Coertjens Mathieu Gruet Leonardo A. Peyré-Tartaruga
author_sort	Gabriela Fischer
title	Factors influencing self-selected walking speed in fibrotic interstitial lung disease
title_short	Factors influencing self-selected walking speed in fibrotic interstitial lung disease
title_full	Factors influencing self-selected walking speed in fibrotic interstitial lung disease
title_fullStr	Factors influencing self-selected walking speed in fibrotic interstitial lung disease
title_full_unstemmed	Factors influencing self-selected walking speed in fibrotic interstitial lung disease
title_sort	factors influencing self-selected walking speed in fibrotic interstitial lung disease
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/5b4fd7023186499ba57f41c4d33917be
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Factors influencing self-selected walking speed in fibrotic interstitial lung disease

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