Virtual memory T cells develop and mediate bystander protective immunity in an IL-15-dependent manner

Virtual memory T cells develop and mediate bystander protective immunity in an IL-15-dependent manner

Virtual memory T cells are CD8 T cells with memory phenotype present in unimmunized mice. Here the authors show that these cells have higher affinity for self-antigen, depend on IL-15 for proliferation and antigen-non-specific cytotoxicity in mice, and that a similar population exists in humans.

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Detalles Bibliográficos
Autores principales: Jason T. White, Eric W. Cross, Matthew A. Burchill, Thomas Danhorn, Martin D. McCarter, Hugo R. Rosen, Brian O’Connor, Ross M. Kedl
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/5b504adf9a774808aa2014fe7ae6ebee
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