Elevation in viral entry genes and innate immunity compromise underlying increased infectivity and severity of COVID-19 in cancer patients
Abstract Multiple studies have reported a doubling in risk of Coronavirus Disease-2019 (COVID-19) among cancer patients. Here, we examine the potential biological rationale behind this recurrent epidemiological observation. By leveraging large-scale genome-wide transcriptional data of normal and mal...
Guardado en:
Autores principales: | Jennifer Yin Yee Kwan, Liang-Tzung Lin, Rachel Bell, Jeffrey P. Bruce, Christopher Richardson, Trevor J. Pugh, Fei-Fei Liu |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/5b5d721bd98047939c6e665fc34c1be2 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Sustained elevation of MG53 in the bloodstream increases tissue regenerative capacity without compromising metabolic function
por: Zehua Bian, et al.
Publicado: (2019) -
Improving defences at the portal of HIV entry: mucosal and innate immunity.
por: Robin J Shattock, et al.
Publicado: (2008) -
Neural stem cell-derived exosomes mediate viral entry
por: Sims B, et al.
Publicado: (2014) -
Rational design of a triple-type human papillomavirus vaccine by compromising viral-type specificity
por: Zhihai Li, et al.
Publicado: (2018) -
Viral enhancer mimicry of host innate-immune promoters.
por: Kai A Kropp, et al.
Publicado: (2014)