Detection of subclonal L1 transductions in colorectal cancer by long-distance inverse-PCR and Nanopore sequencing

Abstract Long interspersed nuclear elements-1 (L1s) are a large family of retrotransposons. Retrotransposons are repetitive sequences that are capable of autonomous mobility via a copy-and-paste mechanism. In most copy events, only the L1 sequence is inserted, however, they can also mobilize the fla...

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Autores principales:	Barun Pradhan, Tatiana Cajuso, Riku Katainen, Päivi Sulo, Tomas Tanskanen, Outi Kilpivaara, Esa Pitkänen, Lauri A. Aaltonen, Liisa Kauppi, Kimmo Palin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Nanopore Sequencing Oxford Nanopore Technologies Long Interspersed Nuclear Elements (LINE) Candidate Insertion Target-primed Reverse Transcription (TPRT) Medicine R Science Q
Acceso en línea:	https://doaj.org/article/5b65de7bdaab4ee0bba34409a6347665
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Detection of subclonal L1 transductions in colorectal cancer by long-distance inverse-PCR and Nanopore sequencing

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