Bone marrow-derived epithelial cells and hair follicle stem cells contribute to development of chronic cutaneous neoplasms

Bone marrow-derived epithelial cells can be recruited to sites of chronic inflammation. Here, the authors using allogenic bone marrow transplantation in a multistage murine cutaneous carcinogenesis model show that bone marrow-derived epithelial cells and hair follicle stem cells are recruited to cut...

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Autores principales: Heuijoon Park, Sonali Lad, Kelsey Boland, Kelly Johnson, Nyssa Readio, Guangchun Jin, Samuel Asfaha, Kelly S. Patterson, Ashok Singh, Xiangdong Yang, Douglas Londono, Anupama Singh, Carol Trempus, Derek Gordon, Timothy C. Wang, Rebecca J. Morris
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/5b74baed5bfe4f80abfd7e5ef800302c
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spelling oai:doaj.org-article:5b74baed5bfe4f80abfd7e5ef800302c2021-12-02T16:49:53ZBone marrow-derived epithelial cells and hair follicle stem cells contribute to development of chronic cutaneous neoplasms10.1038/s41467-018-07688-82041-1723https://doaj.org/article/5b74baed5bfe4f80abfd7e5ef800302c2018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07688-8https://doaj.org/toc/2041-1723Bone marrow-derived epithelial cells can be recruited to sites of chronic inflammation. Here, the authors using allogenic bone marrow transplantation in a multistage murine cutaneous carcinogenesis model show that bone marrow-derived epithelial cells and hair follicle stem cells are recruited to cutaneous neoplasms during tumor promotion of carcinogen-exposed skin and bone marrow.Heuijoon ParkSonali LadKelsey BolandKelly JohnsonNyssa ReadioGuangchun JinSamuel AsfahaKelly S. PattersonAshok SinghXiangdong YangDouglas LondonoAnupama SinghCarol TrempusDerek GordonTimothy C. WangRebecca J. MorrisNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Heuijoon Park
Sonali Lad
Kelsey Boland
Kelly Johnson
Nyssa Readio
Guangchun Jin
Samuel Asfaha
Kelly S. Patterson
Ashok Singh
Xiangdong Yang
Douglas Londono
Anupama Singh
Carol Trempus
Derek Gordon
Timothy C. Wang
Rebecca J. Morris
Bone marrow-derived epithelial cells and hair follicle stem cells contribute to development of chronic cutaneous neoplasms
description Bone marrow-derived epithelial cells can be recruited to sites of chronic inflammation. Here, the authors using allogenic bone marrow transplantation in a multistage murine cutaneous carcinogenesis model show that bone marrow-derived epithelial cells and hair follicle stem cells are recruited to cutaneous neoplasms during tumor promotion of carcinogen-exposed skin and bone marrow.
format article
author Heuijoon Park
Sonali Lad
Kelsey Boland
Kelly Johnson
Nyssa Readio
Guangchun Jin
Samuel Asfaha
Kelly S. Patterson
Ashok Singh
Xiangdong Yang
Douglas Londono
Anupama Singh
Carol Trempus
Derek Gordon
Timothy C. Wang
Rebecca J. Morris
author_facet Heuijoon Park
Sonali Lad
Kelsey Boland
Kelly Johnson
Nyssa Readio
Guangchun Jin
Samuel Asfaha
Kelly S. Patterson
Ashok Singh
Xiangdong Yang
Douglas Londono
Anupama Singh
Carol Trempus
Derek Gordon
Timothy C. Wang
Rebecca J. Morris
author_sort Heuijoon Park
title Bone marrow-derived epithelial cells and hair follicle stem cells contribute to development of chronic cutaneous neoplasms
title_short Bone marrow-derived epithelial cells and hair follicle stem cells contribute to development of chronic cutaneous neoplasms
title_full Bone marrow-derived epithelial cells and hair follicle stem cells contribute to development of chronic cutaneous neoplasms
title_fullStr Bone marrow-derived epithelial cells and hair follicle stem cells contribute to development of chronic cutaneous neoplasms
title_full_unstemmed Bone marrow-derived epithelial cells and hair follicle stem cells contribute to development of chronic cutaneous neoplasms
title_sort bone marrow-derived epithelial cells and hair follicle stem cells contribute to development of chronic cutaneous neoplasms
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/5b74baed5bfe4f80abfd7e5ef800302c
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