Bone marrow-derived epithelial cells and hair follicle stem cells contribute to development of chronic cutaneous neoplasms
Bone marrow-derived epithelial cells can be recruited to sites of chronic inflammation. Here, the authors using allogenic bone marrow transplantation in a multistage murine cutaneous carcinogenesis model show that bone marrow-derived epithelial cells and hair follicle stem cells are recruited to cut...
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Nature Portfolio
2018
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oai:doaj.org-article:5b74baed5bfe4f80abfd7e5ef800302c2021-12-02T16:49:53ZBone marrow-derived epithelial cells and hair follicle stem cells contribute to development of chronic cutaneous neoplasms10.1038/s41467-018-07688-82041-1723https://doaj.org/article/5b74baed5bfe4f80abfd7e5ef800302c2018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07688-8https://doaj.org/toc/2041-1723Bone marrow-derived epithelial cells can be recruited to sites of chronic inflammation. Here, the authors using allogenic bone marrow transplantation in a multistage murine cutaneous carcinogenesis model show that bone marrow-derived epithelial cells and hair follicle stem cells are recruited to cutaneous neoplasms during tumor promotion of carcinogen-exposed skin and bone marrow.Heuijoon ParkSonali LadKelsey BolandKelly JohnsonNyssa ReadioGuangchun JinSamuel AsfahaKelly S. PattersonAshok SinghXiangdong YangDouglas LondonoAnupama SinghCarol TrempusDerek GordonTimothy C. WangRebecca J. MorrisNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018) |
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Science Q Heuijoon Park Sonali Lad Kelsey Boland Kelly Johnson Nyssa Readio Guangchun Jin Samuel Asfaha Kelly S. Patterson Ashok Singh Xiangdong Yang Douglas Londono Anupama Singh Carol Trempus Derek Gordon Timothy C. Wang Rebecca J. Morris Bone marrow-derived epithelial cells and hair follicle stem cells contribute to development of chronic cutaneous neoplasms |
description |
Bone marrow-derived epithelial cells can be recruited to sites of chronic inflammation. Here, the authors using allogenic bone marrow transplantation in a multistage murine cutaneous carcinogenesis model show that bone marrow-derived epithelial cells and hair follicle stem cells are recruited to cutaneous neoplasms during tumor promotion of carcinogen-exposed skin and bone marrow. |
format |
article |
author |
Heuijoon Park Sonali Lad Kelsey Boland Kelly Johnson Nyssa Readio Guangchun Jin Samuel Asfaha Kelly S. Patterson Ashok Singh Xiangdong Yang Douglas Londono Anupama Singh Carol Trempus Derek Gordon Timothy C. Wang Rebecca J. Morris |
author_facet |
Heuijoon Park Sonali Lad Kelsey Boland Kelly Johnson Nyssa Readio Guangchun Jin Samuel Asfaha Kelly S. Patterson Ashok Singh Xiangdong Yang Douglas Londono Anupama Singh Carol Trempus Derek Gordon Timothy C. Wang Rebecca J. Morris |
author_sort |
Heuijoon Park |
title |
Bone marrow-derived epithelial cells and hair follicle stem cells contribute to development of chronic cutaneous neoplasms |
title_short |
Bone marrow-derived epithelial cells and hair follicle stem cells contribute to development of chronic cutaneous neoplasms |
title_full |
Bone marrow-derived epithelial cells and hair follicle stem cells contribute to development of chronic cutaneous neoplasms |
title_fullStr |
Bone marrow-derived epithelial cells and hair follicle stem cells contribute to development of chronic cutaneous neoplasms |
title_full_unstemmed |
Bone marrow-derived epithelial cells and hair follicle stem cells contribute to development of chronic cutaneous neoplasms |
title_sort |
bone marrow-derived epithelial cells and hair follicle stem cells contribute to development of chronic cutaneous neoplasms |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/5b74baed5bfe4f80abfd7e5ef800302c |
work_keys_str_mv |
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