Cytosolic protein delivery using pH-responsive, charge-reversible lipid nanoparticles
Abstract Although proteins have attractive features as biopharmaceuticals, the difficulty in delivering them into the cell interior limits their applicability. Lipid nanoparticles (LNPs) are a promising class of delivery vehicles. When designing a protein delivery system based on LNPs, the major cha...
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Autores principales: | Yusuke Hirai, Hisaaki Hirose, Miki Imanishi, Tomohiro Asai, Shiroh Futaki |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/5b79394d705e4bc08ba13993b49b0bac |
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