A novel method for liquid-phase extraction of cell-free DNA for detection of circulating tumor DNA

Abstract Low yields of extracted cell-free DNA (cfDNA) from plasma limit continued development of liquid biopsy in cancer, especially in early-stage cancer diagnostics and cancer screening applications. We investigate a novel liquid-phase-based DNA isolation method that utilizes aqueous two-phase sy...

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Autores principales: Filip Janku, Helen J. Huang, David Y. Pereira, Masae Kobayashi, Chung Hei Chiu, S. Greg Call, Kristen T. Woodbury, Felix Chao, Daniel R. Marshak, Ricky Y. T. Chiu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/5b8e5b31d9594c7e8e04f5fa388234cc
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