Tissue expression of antigens of ABH blood groups in species of New World Monkeys (Aotus infulatus, Callithrix jacchus, Sapajus apella and Saimiri sciureus).

ABH antigens are histo-antigens, but were first described on the surface of human erythrocytes. They are found in those cells only in great apes and humans, while in more primitive animals they are found in tissues and body fluids. ABH antigens are mainly distributed in tissues that are in contact w...

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Autores principales:	Délia Cristina Figueira Aguiar, Washington Luiz Assunção Pereira, Gyselly de Cássia Bastos de Matos, Klena Sarges Marruaz da Silva, Rosane do Socorro Pompeu de Loiola, Tereza Cristina Oliveira Corvelo
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2020
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/5b930b76a10b4962a86cad8151232058
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spelling	oai:doaj.org-article:5b930b76a10b4962a86cad81512320582021-12-02T20:05:45ZTissue expression of antigens of ABH blood groups in species of New World Monkeys (Aotus infulatus, Callithrix jacchus, Sapajus apella and Saimiri sciureus).1932-620310.1371/journal.pone.0241487https://doaj.org/article/5b930b76a10b4962a86cad81512320582020-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0241487https://doaj.org/toc/1932-6203ABH antigens are histo-antigens, but were first described on the surface of human erythrocytes. They are found in those cells only in great apes and humans, while in more primitive animals they are found in tissues and body fluids. ABH antigens are mainly distributed in tissues that are in contact with the external environment and may serve as ligands for pathogens in tissues or block their connection. Description of the distribution of these molecules in non-human primate tissues is restricted to a few tissues and species. This paper describes the expression of human A, B and H type antigens in different organs from four species of New World Primates, obtained from the Centro Nacional de Primatas, as well as comparing that expression with what has been described for humans. In this study, although the tissue description of the antigens is similar to the genetic model for humans, some differences in expression between some organs from those species and those of humans were found. The differences occurred mainly in endodermal organs that have secretory functions and are probably under the control of the human-type FUT-2 enzyme. In the mesodermal-origin organs there was a reduction or absence of A and B antigen marking, particularly in the H precursor substance, indicating that those organs are under the control of the human-type FUT-1 enzyme. These findings have demonstrated that there is similar ABH antigen reactivity in tissue distribution between the species, although there are some species-specific cases.Délia Cristina Figueira AguiarWashington Luiz Assunção PereiraGyselly de Cássia Bastos de MatosKlena Sarges Marruaz da SilvaRosane do Socorro Pompeu de LoiolaTereza Cristina Oliveira CorveloPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 15, Iss 11, p e0241487 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Délia Cristina Figueira Aguiar Washington Luiz Assunção Pereira Gyselly de Cássia Bastos de Matos Klena Sarges Marruaz da Silva Rosane do Socorro Pompeu de Loiola Tereza Cristina Oliveira Corvelo Tissue expression of antigens of ABH blood groups in species of New World Monkeys (Aotus infulatus, Callithrix jacchus, Sapajus apella and Saimiri sciureus).
description	ABH antigens are histo-antigens, but were first described on the surface of human erythrocytes. They are found in those cells only in great apes and humans, while in more primitive animals they are found in tissues and body fluids. ABH antigens are mainly distributed in tissues that are in contact with the external environment and may serve as ligands for pathogens in tissues or block their connection. Description of the distribution of these molecules in non-human primate tissues is restricted to a few tissues and species. This paper describes the expression of human A, B and H type antigens in different organs from four species of New World Primates, obtained from the Centro Nacional de Primatas, as well as comparing that expression with what has been described for humans. In this study, although the tissue description of the antigens is similar to the genetic model for humans, some differences in expression between some organs from those species and those of humans were found. The differences occurred mainly in endodermal organs that have secretory functions and are probably under the control of the human-type FUT-2 enzyme. In the mesodermal-origin organs there was a reduction or absence of A and B antigen marking, particularly in the H precursor substance, indicating that those organs are under the control of the human-type FUT-1 enzyme. These findings have demonstrated that there is similar ABH antigen reactivity in tissue distribution between the species, although there are some species-specific cases.
format	article
author	Délia Cristina Figueira Aguiar Washington Luiz Assunção Pereira Gyselly de Cássia Bastos de Matos Klena Sarges Marruaz da Silva Rosane do Socorro Pompeu de Loiola Tereza Cristina Oliveira Corvelo
author_facet	Délia Cristina Figueira Aguiar Washington Luiz Assunção Pereira Gyselly de Cássia Bastos de Matos Klena Sarges Marruaz da Silva Rosane do Socorro Pompeu de Loiola Tereza Cristina Oliveira Corvelo
author_sort	Délia Cristina Figueira Aguiar
title	Tissue expression of antigens of ABH blood groups in species of New World Monkeys (Aotus infulatus, Callithrix jacchus, Sapajus apella and Saimiri sciureus).
title_short	Tissue expression of antigens of ABH blood groups in species of New World Monkeys (Aotus infulatus, Callithrix jacchus, Sapajus apella and Saimiri sciureus).
title_full	Tissue expression of antigens of ABH blood groups in species of New World Monkeys (Aotus infulatus, Callithrix jacchus, Sapajus apella and Saimiri sciureus).
title_fullStr	Tissue expression of antigens of ABH blood groups in species of New World Monkeys (Aotus infulatus, Callithrix jacchus, Sapajus apella and Saimiri sciureus).
title_full_unstemmed	Tissue expression of antigens of ABH blood groups in species of New World Monkeys (Aotus infulatus, Callithrix jacchus, Sapajus apella and Saimiri sciureus).
title_sort	tissue expression of antigens of abh blood groups in species of new world monkeys (aotus infulatus, callithrix jacchus, sapajus apella and saimiri sciureus).
publisher	Public Library of Science (PLoS)
publishDate	2020
url	https://doaj.org/article/5b930b76a10b4962a86cad8151232058
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Tissue expression of antigens of ABH blood groups in species of New World Monkeys (Aotus infulatus, Callithrix jacchus, Sapajus apella and Saimiri sciureus).

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