Complications and management of coagulation disorders in leukemia patients

Deepesh Lad, Arihant Jain, Subhash Varma Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India Abstract: Patients with leukemia are predisposed to various coagulation abnormalities. Thrombosis and bleeding continue to be a majo...

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Autores principales:	Lad DP, Jain A, Varma S
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2017
Materias:	leukemia coagulation thrombosis bleeding Diseases of the blood and blood-forming organs RC633-647.5
Acceso en línea:	https://doaj.org/article/5b937e9404e841929f71d1540e7105be
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spelling	oai:doaj.org-article:5b937e9404e841929f71d1540e7105be2021-12-02T01:12:04ZComplications and management of coagulation disorders in leukemia patients1179-9889https://doaj.org/article/5b937e9404e841929f71d1540e7105be2017-09-01T00:00:00Zhttps://www.dovepress.com/complications-and-management-of-coagulation-disorders-in-leukemia-pati-peer-reviewed-article-BLCTThttps://doaj.org/toc/1179-9889Deepesh Lad, Arihant Jain, Subhash Varma Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India Abstract: Patients with leukemia are predisposed to various coagulation abnormalities. Thrombosis and bleeding continue to be a major cause of morbidity and mortality in leukemias. The pathophysiology of these disorders is unique, and not only the disease but also the treatment and other factors play a role. There has been an increase in the understanding of these disorders in leukemias. However, it is still difficult to predict when and which patients will have these complications. The evidence for the management of coagulation abnormalities in leukemias is still evolving and not as established as in solid malignancies. The management of these disorders is complex, and making clinical decisions is often challenging. In the era of specialization, where there are different hematologists looking after benign- and malignant-hematology patients, opinions of thrombosis experts are often sought by leukemia specialists. This review aims to bridge the gap in the knowledge of these disorders between these specialists. Keywords: leukemia, coagulation, thrombosis, bleedingLad DPJain AVarma SDove Medical PressarticleleukemiacoagulationthrombosisbleedingDiseases of the blood and blood-forming organsRC633-647.5ENBlood and Lymphatic Cancer: Targets and Therapy, Vol Volume 7, Pp 61-72 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	leukemia coagulation thrombosis bleeding Diseases of the blood and blood-forming organs RC633-647.5
spellingShingle	leukemia coagulation thrombosis bleeding Diseases of the blood and blood-forming organs RC633-647.5 Lad DP Jain A Varma S Complications and management of coagulation disorders in leukemia patients
description	Deepesh Lad, Arihant Jain, Subhash Varma Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India Abstract: Patients with leukemia are predisposed to various coagulation abnormalities. Thrombosis and bleeding continue to be a major cause of morbidity and mortality in leukemias. The pathophysiology of these disorders is unique, and not only the disease but also the treatment and other factors play a role. There has been an increase in the understanding of these disorders in leukemias. However, it is still difficult to predict when and which patients will have these complications. The evidence for the management of coagulation abnormalities in leukemias is still evolving and not as established as in solid malignancies. The management of these disorders is complex, and making clinical decisions is often challenging. In the era of specialization, where there are different hematologists looking after benign- and malignant-hematology patients, opinions of thrombosis experts are often sought by leukemia specialists. This review aims to bridge the gap in the knowledge of these disorders between these specialists. Keywords: leukemia, coagulation, thrombosis, bleeding
format	article
author	Lad DP Jain A Varma S
author_facet	Lad DP Jain A Varma S
author_sort	Lad DP
title	Complications and management of coagulation disorders in leukemia patients
title_short	Complications and management of coagulation disorders in leukemia patients
title_full	Complications and management of coagulation disorders in leukemia patients
title_fullStr	Complications and management of coagulation disorders in leukemia patients
title_full_unstemmed	Complications and management of coagulation disorders in leukemia patients
title_sort	complications and management of coagulation disorders in leukemia patients
publisher	Dove Medical Press
publishDate	2017
url	https://doaj.org/article/5b937e9404e841929f71d1540e7105be
work_keys_str_mv	AT laddp complicationsandmanagementofcoagulationdisordersinleukemiapatients AT jaina complicationsandmanagementofcoagulationdisordersinleukemiapatients AT varmas complicationsandmanagementofcoagulationdisordersinleukemiapatients
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Complications and management of coagulation disorders in leukemia patients

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