Functionalized azetidines via visible light-enabled aza Paternò-Büchi reactions
The Aza Paternò-Büchi reaction is arguably among the most direct approaches to functionalized azetidines, which are common medicinal scaffolds. Here, the authors report a mild and selective visible light-enabled intramolecular aza Paternò-Büchi reaction yielding bicyclic azetidines in high yields an...
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Nature Portfolio
2019
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oai:doaj.org-article:5b94bd99ca7649488389d44b9b8bbe692021-12-02T16:57:24ZFunctionalized azetidines via visible light-enabled aza Paternò-Büchi reactions10.1038/s41467-019-13072-x2041-1723https://doaj.org/article/5b94bd99ca7649488389d44b9b8bbe692019-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13072-xhttps://doaj.org/toc/2041-1723The Aza Paternò-Büchi reaction is arguably among the most direct approaches to functionalized azetidines, which are common medicinal scaffolds. Here, the authors report a mild and selective visible light-enabled intramolecular aza Paternò-Büchi reaction yielding bicyclic azetidines in high yields and diastereoselectivity.Marc R. BeckerAlistair D. RichardsonCorinna S. SchindlerNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-8 (2019) |
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Science Q Marc R. Becker Alistair D. Richardson Corinna S. Schindler Functionalized azetidines via visible light-enabled aza Paternò-Büchi reactions |
description |
The Aza Paternò-Büchi reaction is arguably among the most direct approaches to functionalized azetidines, which are common medicinal scaffolds. Here, the authors report a mild and selective visible light-enabled intramolecular aza Paternò-Büchi reaction yielding bicyclic azetidines in high yields and diastereoselectivity. |
format |
article |
author |
Marc R. Becker Alistair D. Richardson Corinna S. Schindler |
author_facet |
Marc R. Becker Alistair D. Richardson Corinna S. Schindler |
author_sort |
Marc R. Becker |
title |
Functionalized azetidines via visible light-enabled aza Paternò-Büchi reactions |
title_short |
Functionalized azetidines via visible light-enabled aza Paternò-Büchi reactions |
title_full |
Functionalized azetidines via visible light-enabled aza Paternò-Büchi reactions |
title_fullStr |
Functionalized azetidines via visible light-enabled aza Paternò-Büchi reactions |
title_full_unstemmed |
Functionalized azetidines via visible light-enabled aza Paternò-Büchi reactions |
title_sort |
functionalized azetidines via visible light-enabled aza paternò-büchi reactions |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/5b94bd99ca7649488389d44b9b8bbe69 |
work_keys_str_mv |
AT marcrbecker functionalizedazetidinesviavisiblelightenabledazapaternobuchireactions AT alistairdrichardson functionalizedazetidinesviavisiblelightenabledazapaternobuchireactions AT corinnasschindler functionalizedazetidinesviavisiblelightenabledazapaternobuchireactions |
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