A broad analysis of splicing regulation in yeast using a large library of synthetic introns.

RNA splicing is a key process in eukaryotic gene expression, in which an intron is spliced out of a pre-mRNA molecule to eventually produce a mature mRNA. Most intron-containing genes are constitutively spliced, hence efficient splicing of an intron is crucial for efficient regulation of gene expres...

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Bibliographic Details
Main Authors: Dvir Schirman, Zohar Yakhini, Yitzhak Pilpel, Orna Dahan
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2021
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Online Access:https://doaj.org/article/5ba94e676d774c43b1a50c724747047d
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