Small molecule screen in embryonic zebrafish using modular variations to target segmentation

Chemical screens can identify small molecules that affect biological development, with potential therapeutic value. Here, the authors use a modular approach in a screen in zebrafish embryos, varying concentration, genotype and timing to target segmentation disorders, birth defects that affect the sp...

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Autores principales:	Sandra Richter, Ulrike Schulze, Pavel Tomançak, Andrew C. Oates
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/5bae9903a80946e59f02a1b3b1705726
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spelling	oai:doaj.org-article:5bae9903a80946e59f02a1b3b17057262021-12-02T17:06:30ZSmall molecule screen in embryonic zebrafish using modular variations to target segmentation10.1038/s41467-017-01469-52041-1723https://doaj.org/article/5bae9903a80946e59f02a1b3b17057262017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01469-5https://doaj.org/toc/2041-1723Chemical screens can identify small molecules that affect biological development, with potential therapeutic value. Here, the authors use a modular approach in a screen in zebrafish embryos, varying concentration, genotype and timing to target segmentation disorders, birth defects that affect the spinal column.Sandra RichterUlrike SchulzePavel TomançakAndrew C. OatesNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sandra Richter Ulrike Schulze Pavel Tomançak Andrew C. Oates Small molecule screen in embryonic zebrafish using modular variations to target segmentation
description	Chemical screens can identify small molecules that affect biological development, with potential therapeutic value. Here, the authors use a modular approach in a screen in zebrafish embryos, varying concentration, genotype and timing to target segmentation disorders, birth defects that affect the spinal column.
format	article
author	Sandra Richter Ulrike Schulze Pavel Tomançak Andrew C. Oates
author_facet	Sandra Richter Ulrike Schulze Pavel Tomançak Andrew C. Oates
author_sort	Sandra Richter
title	Small molecule screen in embryonic zebrafish using modular variations to target segmentation
title_short	Small molecule screen in embryonic zebrafish using modular variations to target segmentation
title_full	Small molecule screen in embryonic zebrafish using modular variations to target segmentation
title_fullStr	Small molecule screen in embryonic zebrafish using modular variations to target segmentation
title_full_unstemmed	Small molecule screen in embryonic zebrafish using modular variations to target segmentation
title_sort	small molecule screen in embryonic zebrafish using modular variations to target segmentation
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/5bae9903a80946e59f02a1b3b1705726
work_keys_str_mv	AT sandrarichter smallmoleculescreeninembryoniczebrafishusingmodularvariationstotargetsegmentation AT ulrikeschulze smallmoleculescreeninembryoniczebrafishusingmodularvariationstotargetsegmentation AT paveltomancak smallmoleculescreeninembryoniczebrafishusingmodularvariationstotargetsegmentation AT andrewcoates smallmoleculescreeninembryoniczebrafishusingmodularvariationstotargetsegmentation
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Small molecule screen in embryonic zebrafish using modular variations to target segmentation

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