Chronic IL9 and IL-13 exposure leads to an altered differentiation of ciliated cells in a well-differentiated paediatric bronchial epithelial cell model.
Asthma is a chronic inflammatory disease characterised by airways remodelling. In mouse models IL-9 and IL-13 have been implicated in airways remodelling including mucus hypersecretion and goblet cell hyperplasia. Their role, especially that of IL-9, has been much less studied in authentic human ex...
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Autores principales: | Jeremy C Parker, Surendran Thavagnanam, Grzegorz Skibinski, Jeremy Lyons, Jennifer Bell, Liam G Heaney, Michael D Shields |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/5bb2d40dc8944e4ba251ac5f51bc8b24 |
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