Non-coding RNAs participate in the regulatory network of CLDN4 via ceRNA mediated miRNA evasion

Non-coding RNAs can modify the expression of proteins in cancer networks. Here the authors reveal a regulatory network in gastric cancer whereby claudin-4 expression is reduced by specific miRNAs, which are in turn bound by specific lncRNAs acting as competing endogenous RNAs (ceRNAs), resulting in...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Yong-xi Song, Jing-xu Sun, Jun-hua Zhao, Yu-chong Yang, Jin-xin Shi, Zhong-hua Wu, Xiao-wan Chen, Peng Gao, Zhi-feng Miao, Zhen-ning Wang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/5bb788f0382e4a9eb70dc17babb353b2
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:5bb788f0382e4a9eb70dc17babb353b2
record_format	dspace
spelling	oai:doaj.org-article:5bb788f0382e4a9eb70dc17babb353b22021-12-02T10:48:10ZNon-coding RNAs participate in the regulatory network of CLDN4 via ceRNA mediated miRNA evasion10.1038/s41467-017-00304-12041-1723https://doaj.org/article/5bb788f0382e4a9eb70dc17babb353b22017-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00304-1https://doaj.org/toc/2041-1723Non-coding RNAs can modify the expression of proteins in cancer networks. Here the authors reveal a regulatory network in gastric cancer whereby claudin-4 expression is reduced by specific miRNAs, which are in turn bound by specific lncRNAs acting as competing endogenous RNAs (ceRNAs), resulting in increased claudin-4 expression.Yong-xi SongJing-xu SunJun-hua ZhaoYu-chong YangJin-xin ShiZhong-hua WuXiao-wan ChenPeng GaoZhi-feng MiaoZhen-ning WangNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yong-xi Song Jing-xu Sun Jun-hua Zhao Yu-chong Yang Jin-xin Shi Zhong-hua Wu Xiao-wan Chen Peng Gao Zhi-feng Miao Zhen-ning Wang Non-coding RNAs participate in the regulatory network of CLDN4 via ceRNA mediated miRNA evasion
description	Non-coding RNAs can modify the expression of proteins in cancer networks. Here the authors reveal a regulatory network in gastric cancer whereby claudin-4 expression is reduced by specific miRNAs, which are in turn bound by specific lncRNAs acting as competing endogenous RNAs (ceRNAs), resulting in increased claudin-4 expression.
format	article
author	Yong-xi Song Jing-xu Sun Jun-hua Zhao Yu-chong Yang Jin-xin Shi Zhong-hua Wu Xiao-wan Chen Peng Gao Zhi-feng Miao Zhen-ning Wang
author_facet	Yong-xi Song Jing-xu Sun Jun-hua Zhao Yu-chong Yang Jin-xin Shi Zhong-hua Wu Xiao-wan Chen Peng Gao Zhi-feng Miao Zhen-ning Wang
author_sort	Yong-xi Song
title	Non-coding RNAs participate in the regulatory network of CLDN4 via ceRNA mediated miRNA evasion
title_short	Non-coding RNAs participate in the regulatory network of CLDN4 via ceRNA mediated miRNA evasion
title_full	Non-coding RNAs participate in the regulatory network of CLDN4 via ceRNA mediated miRNA evasion
title_fullStr	Non-coding RNAs participate in the regulatory network of CLDN4 via ceRNA mediated miRNA evasion
title_full_unstemmed	Non-coding RNAs participate in the regulatory network of CLDN4 via ceRNA mediated miRNA evasion
title_sort	non-coding rnas participate in the regulatory network of cldn4 via cerna mediated mirna evasion
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/5bb788f0382e4a9eb70dc17babb353b2
work_keys_str_mv	AT yongxisong noncodingrnasparticipateintheregulatorynetworkofcldn4viacernamediatedmirnaevasion AT jingxusun noncodingrnasparticipateintheregulatorynetworkofcldn4viacernamediatedmirnaevasion AT junhuazhao noncodingrnasparticipateintheregulatorynetworkofcldn4viacernamediatedmirnaevasion AT yuchongyang noncodingrnasparticipateintheregulatorynetworkofcldn4viacernamediatedmirnaevasion AT jinxinshi noncodingrnasparticipateintheregulatorynetworkofcldn4viacernamediatedmirnaevasion AT zhonghuawu noncodingrnasparticipateintheregulatorynetworkofcldn4viacernamediatedmirnaevasion AT xiaowanchen noncodingrnasparticipateintheregulatorynetworkofcldn4viacernamediatedmirnaevasion AT penggao noncodingrnasparticipateintheregulatorynetworkofcldn4viacernamediatedmirnaevasion AT zhifengmiao noncodingrnasparticipateintheregulatorynetworkofcldn4viacernamediatedmirnaevasion AT zhenningwang noncodingrnasparticipateintheregulatorynetworkofcldn4viacernamediatedmirnaevasion
_version_	1718396647844610048

Non-coding RNAs participate in the regulatory network of CLDN4 via ceRNA mediated miRNA evasion

Ejemplares similares