HTNV infection of CD8+ T cells is associated with disease progression in HFRS patients

Rongrong Liu et al. find that Hantaan virus, a common cause of hemorrhagic fever with renal syndrome (HFRS) in China, can infect CD8+ T cells and that these cells can support the full viral replication cycle. They also see an association between CD8+ T cells infection and disease progression in HFRS...

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Autores principales: Rongrong Liu, Ruixue Ma, Ziyu Liu, Haifeng Hu, Jiayi Shu, Peizhen Hu, Junjun Kang, Yusi Zhang, Mingwei Han, Xiaoxiao Zhang, Yiting Zheng, Qikang Ying, Shiyuan Hou, Wenqiu Wang, Fang Wang, Ning Cheng, Yan Zhuang, Jianqi Lian, Xia Jin, Xingan Wu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/5bc584b61789445782cbe26f90784bc1
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spelling oai:doaj.org-article:5bc584b61789445782cbe26f90784bc12021-12-02T18:24:52ZHTNV infection of CD8+ T cells is associated with disease progression in HFRS patients10.1038/s42003-021-02182-22399-3642https://doaj.org/article/5bc584b61789445782cbe26f90784bc12021-06-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02182-2https://doaj.org/toc/2399-3642Rongrong Liu et al. find that Hantaan virus, a common cause of hemorrhagic fever with renal syndrome (HFRS) in China, can infect CD8+ T cells and that these cells can support the full viral replication cycle. They also see an association between CD8+ T cells infection and disease progression in HFRS patients.Rongrong LiuRuixue MaZiyu LiuHaifeng HuJiayi ShuPeizhen HuJunjun KangYusi ZhangMingwei HanXiaoxiao ZhangYiting ZhengQikang YingShiyuan HouWenqiu WangFang WangNing ChengYan ZhuangJianqi LianXia JinXingan WuNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Rongrong Liu
Ruixue Ma
Ziyu Liu
Haifeng Hu
Jiayi Shu
Peizhen Hu
Junjun Kang
Yusi Zhang
Mingwei Han
Xiaoxiao Zhang
Yiting Zheng
Qikang Ying
Shiyuan Hou
Wenqiu Wang
Fang Wang
Ning Cheng
Yan Zhuang
Jianqi Lian
Xia Jin
Xingan Wu
HTNV infection of CD8+ T cells is associated with disease progression in HFRS patients
description Rongrong Liu et al. find that Hantaan virus, a common cause of hemorrhagic fever with renal syndrome (HFRS) in China, can infect CD8+ T cells and that these cells can support the full viral replication cycle. They also see an association between CD8+ T cells infection and disease progression in HFRS patients.
format article
author Rongrong Liu
Ruixue Ma
Ziyu Liu
Haifeng Hu
Jiayi Shu
Peizhen Hu
Junjun Kang
Yusi Zhang
Mingwei Han
Xiaoxiao Zhang
Yiting Zheng
Qikang Ying
Shiyuan Hou
Wenqiu Wang
Fang Wang
Ning Cheng
Yan Zhuang
Jianqi Lian
Xia Jin
Xingan Wu
author_facet Rongrong Liu
Ruixue Ma
Ziyu Liu
Haifeng Hu
Jiayi Shu
Peizhen Hu
Junjun Kang
Yusi Zhang
Mingwei Han
Xiaoxiao Zhang
Yiting Zheng
Qikang Ying
Shiyuan Hou
Wenqiu Wang
Fang Wang
Ning Cheng
Yan Zhuang
Jianqi Lian
Xia Jin
Xingan Wu
author_sort Rongrong Liu
title HTNV infection of CD8+ T cells is associated with disease progression in HFRS patients
title_short HTNV infection of CD8+ T cells is associated with disease progression in HFRS patients
title_full HTNV infection of CD8+ T cells is associated with disease progression in HFRS patients
title_fullStr HTNV infection of CD8+ T cells is associated with disease progression in HFRS patients
title_full_unstemmed HTNV infection of CD8+ T cells is associated with disease progression in HFRS patients
title_sort htnv infection of cd8+ t cells is associated with disease progression in hfrs patients
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/5bc584b61789445782cbe26f90784bc1
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