Structural analogues in herbal medicine ginseng hit a shared target to achieve cumulative bioactivity

Zhang et al. design ginsenoside structural analogues and demonstrate that their combination shows more potent immunomodulatory activities than individual ginsenosides used alone at the same dosages. They predict that these analogues act on the joint target NLRP3 and consequently suggest that structu...

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Autores principales:	Wei Zhang, Wei-Wei Tao, Jing Zhou, Cheng-Ying Wu, Fang Long, Hong Shen, He Zhu, Qian Mao, Jun Xu, Song-Lin Li, Qi-Nan Wu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/5bcd708329c044c0ae987350bedcfee2
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spelling	oai:doaj.org-article:5bcd708329c044c0ae987350bedcfee22021-12-02T16:57:13ZStructural analogues in herbal medicine ginseng hit a shared target to achieve cumulative bioactivity10.1038/s42003-021-02084-32399-3642https://doaj.org/article/5bcd708329c044c0ae987350bedcfee22021-05-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02084-3https://doaj.org/toc/2399-3642Zhang et al. design ginsenoside structural analogues and demonstrate that their combination shows more potent immunomodulatory activities than individual ginsenosides used alone at the same dosages. They predict that these analogues act on the joint target NLRP3 and consequently suggest that structural analogues hit a shared target to achieve cumulative bioactivity.Wei ZhangWei-Wei TaoJing ZhouCheng-Ying WuFang LongHong ShenHe ZhuQian MaoJun XuSong-Lin LiQi-Nan WuNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Wei Zhang Wei-Wei Tao Jing Zhou Cheng-Ying Wu Fang Long Hong Shen He Zhu Qian Mao Jun Xu Song-Lin Li Qi-Nan Wu Structural analogues in herbal medicine ginseng hit a shared target to achieve cumulative bioactivity
description	Zhang et al. design ginsenoside structural analogues and demonstrate that their combination shows more potent immunomodulatory activities than individual ginsenosides used alone at the same dosages. They predict that these analogues act on the joint target NLRP3 and consequently suggest that structural analogues hit a shared target to achieve cumulative bioactivity.
format	article
author	Wei Zhang Wei-Wei Tao Jing Zhou Cheng-Ying Wu Fang Long Hong Shen He Zhu Qian Mao Jun Xu Song-Lin Li Qi-Nan Wu
author_facet	Wei Zhang Wei-Wei Tao Jing Zhou Cheng-Ying Wu Fang Long Hong Shen He Zhu Qian Mao Jun Xu Song-Lin Li Qi-Nan Wu
author_sort	Wei Zhang
title	Structural analogues in herbal medicine ginseng hit a shared target to achieve cumulative bioactivity
title_short	Structural analogues in herbal medicine ginseng hit a shared target to achieve cumulative bioactivity
title_full	Structural analogues in herbal medicine ginseng hit a shared target to achieve cumulative bioactivity
title_fullStr	Structural analogues in herbal medicine ginseng hit a shared target to achieve cumulative bioactivity
title_full_unstemmed	Structural analogues in herbal medicine ginseng hit a shared target to achieve cumulative bioactivity
title_sort	structural analogues in herbal medicine ginseng hit a shared target to achieve cumulative bioactivity
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/5bcd708329c044c0ae987350bedcfee2
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Structural analogues in herbal medicine ginseng hit a shared target to achieve cumulative bioactivity

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