Timing the initiation of multiple myeloma

The initial mutational processes and how these lead to progression in multiple myeloma (MM) are unclear. Here, the authors identify mutational signatures that occur over time in a large cohort of MM patients and suggest features that may help in early diagnosis.

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Autores principales:	Even H. Rustad, Venkata Yellapantula, Daniel Leongamornlert, Niccolò Bolli, Guy Ledergor, Ferran Nadeu, Nicos Angelopoulos, Kevin J. Dawson, Thomas J. Mitchell, Robert J. Osborne, Bachisio Ziccheddu, Cristiana Carniti, Vittorio Montefusco, Paolo Corradini, Kenneth C. Anderson, Philippe Moreau, Elli Papaemmanuil, Ludmil B. Alexandrov, Xose S. Puente, Elias Campo, Reiner Siebert, Herve Avet-Loiseau, Ola Landgren, Nikhil Munshi, Peter J. Campbell, Francesco Maura
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/5bcecbd98cdc4f9fbf76239987880049
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spelling	oai:doaj.org-article:5bcecbd98cdc4f9fbf762399878800492021-12-02T15:39:08ZTiming the initiation of multiple myeloma10.1038/s41467-020-15740-92041-1723https://doaj.org/article/5bcecbd98cdc4f9fbf762399878800492020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15740-9https://doaj.org/toc/2041-1723The initial mutational processes and how these lead to progression in multiple myeloma (MM) are unclear. Here, the authors identify mutational signatures that occur over time in a large cohort of MM patients and suggest features that may help in early diagnosis.Even H. RustadVenkata YellapantulaDaniel LeongamornlertNiccolò BolliGuy LedergorFerran NadeuNicos AngelopoulosKevin J. DawsonThomas J. MitchellRobert J. OsborneBachisio ZicchedduCristiana CarnitiVittorio MontefuscoPaolo CorradiniKenneth C. AndersonPhilippe MoreauElli PapaemmanuilLudmil B. AlexandrovXose S. PuenteElias CampoReiner SiebertHerve Avet-LoiseauOla LandgrenNikhil MunshiPeter J. CampbellFrancesco MauraNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Even H. Rustad Venkata Yellapantula Daniel Leongamornlert Niccolò Bolli Guy Ledergor Ferran Nadeu Nicos Angelopoulos Kevin J. Dawson Thomas J. Mitchell Robert J. Osborne Bachisio Ziccheddu Cristiana Carniti Vittorio Montefusco Paolo Corradini Kenneth C. Anderson Philippe Moreau Elli Papaemmanuil Ludmil B. Alexandrov Xose S. Puente Elias Campo Reiner Siebert Herve Avet-Loiseau Ola Landgren Nikhil Munshi Peter J. Campbell Francesco Maura Timing the initiation of multiple myeloma
description	The initial mutational processes and how these lead to progression in multiple myeloma (MM) are unclear. Here, the authors identify mutational signatures that occur over time in a large cohort of MM patients and suggest features that may help in early diagnosis.
format	article
author	Even H. Rustad Venkata Yellapantula Daniel Leongamornlert Niccolò Bolli Guy Ledergor Ferran Nadeu Nicos Angelopoulos Kevin J. Dawson Thomas J. Mitchell Robert J. Osborne Bachisio Ziccheddu Cristiana Carniti Vittorio Montefusco Paolo Corradini Kenneth C. Anderson Philippe Moreau Elli Papaemmanuil Ludmil B. Alexandrov Xose S. Puente Elias Campo Reiner Siebert Herve Avet-Loiseau Ola Landgren Nikhil Munshi Peter J. Campbell Francesco Maura
author_facet	Even H. Rustad Venkata Yellapantula Daniel Leongamornlert Niccolò Bolli Guy Ledergor Ferran Nadeu Nicos Angelopoulos Kevin J. Dawson Thomas J. Mitchell Robert J. Osborne Bachisio Ziccheddu Cristiana Carniti Vittorio Montefusco Paolo Corradini Kenneth C. Anderson Philippe Moreau Elli Papaemmanuil Ludmil B. Alexandrov Xose S. Puente Elias Campo Reiner Siebert Herve Avet-Loiseau Ola Landgren Nikhil Munshi Peter J. Campbell Francesco Maura
author_sort	Even H. Rustad
title	Timing the initiation of multiple myeloma
title_short	Timing the initiation of multiple myeloma
title_full	Timing the initiation of multiple myeloma
title_fullStr	Timing the initiation of multiple myeloma
title_full_unstemmed	Timing the initiation of multiple myeloma
title_sort	timing the initiation of multiple myeloma
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/5bcecbd98cdc4f9fbf76239987880049
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Timing the initiation of multiple myeloma

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