Incidence and predictors of mortality among patients with head injury admitted to Hawassa University Comprehensive Specialized Hospital, Southern Ethiopia: A retrospective follow-up study.

<h4>Introduction</h4>Head injury is the leading cause of morbidity and mortality throughout the world, especially in resource-limited countries including Ethiopia. However, little is known about the mortality rate and its predictors among these patients in Ethiopia. Thus, the study aims...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Desalegn Dawit Assele, Tigabu Addisu Lendado, Merid Assefa Awato, Shimelash Bitew Workie, Wolde Facha Faltamo
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/5bd5e3ece3b1428ba9da045e49a5b00e
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:5bd5e3ece3b1428ba9da045e49a5b00e
record_format	dspace
spelling	oai:doaj.org-article:5bd5e3ece3b1428ba9da045e49a5b00e2021-12-02T20:14:58ZIncidence and predictors of mortality among patients with head injury admitted to Hawassa University Comprehensive Specialized Hospital, Southern Ethiopia: A retrospective follow-up study.1932-620310.1371/journal.pone.0254245https://doaj.org/article/5bd5e3ece3b1428ba9da045e49a5b00e2021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0254245https://doaj.org/toc/1932-6203<h4>Introduction</h4>Head injury is the leading cause of morbidity and mortality throughout the world, especially in resource-limited countries including Ethiopia. However, little is known about the mortality rate and its predictors among these patients in Ethiopia. Thus, the study aims to assess the incidence rate of mortality and its predictors among patients with head injury admitted at Hawassa University Comprehensive Specialized Hospital.<h4>Methods</h4>Institutional based retrospective follow-up study was conducted among 1220 randomly selected head injury patients admitted from July 2017 to July 2019. Bivariable and multivariable Cox regression models were fitted to identify the predictors of mortality. Proportionality assumption was tested by a global test based on the Schoenfeld residuals test.<h4>Results</h4>The incidence of the mortality rate was 2.26 (95%CI: 1.9-2.6) per 100-person day observation. The independent predictors of time to death were age above 65 years (AHR:3.49, 95%CI:1.63, 7.48), severe TBI (AHR: 8.8, 95%CI:5.13, 15.0), moderate TBI (AHR:3, 95%CI:1.73,5.31), hypotension (AHR:1.72, 95%CI: 1.11,2.66), hypoxia (AHR:1.92, 95%CI: 1.33,2.76), hyperthermia (AHR:1.8, 95%CI: 1.23,2.63) and hypoglycemic (AHR:1.94, 95%CI: 1.34, 2.81) positively associated with mortality, while underwent neurosurgery was negatively associated with mortality (AHR: 0.25, 95% CI: 0.11,0.53).<h4>Conclusion</h4>The incidence of mortality rate among head injury patients was high. Older age, moderate and severe TBI, hypotension and hypoxia at admission, neurosurgical procedure, and the episode of hyperthermia and hypoglycemia during hospitalization were the independent predictors of mortality among head injury patients. Therefore, intervention to reduce earlier deaths should focus on the prevention of secondary brain insults.Desalegn Dawit AsseleTigabu Addisu LendadoMerid Assefa AwatoShimelash Bitew WorkieWolde Facha FaltamoPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 8, p e0254245 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Desalegn Dawit Assele Tigabu Addisu Lendado Merid Assefa Awato Shimelash Bitew Workie Wolde Facha Faltamo Incidence and predictors of mortality among patients with head injury admitted to Hawassa University Comprehensive Specialized Hospital, Southern Ethiopia: A retrospective follow-up study.
description	<h4>Introduction</h4>Head injury is the leading cause of morbidity and mortality throughout the world, especially in resource-limited countries including Ethiopia. However, little is known about the mortality rate and its predictors among these patients in Ethiopia. Thus, the study aims to assess the incidence rate of mortality and its predictors among patients with head injury admitted at Hawassa University Comprehensive Specialized Hospital.<h4>Methods</h4>Institutional based retrospective follow-up study was conducted among 1220 randomly selected head injury patients admitted from July 2017 to July 2019. Bivariable and multivariable Cox regression models were fitted to identify the predictors of mortality. Proportionality assumption was tested by a global test based on the Schoenfeld residuals test.<h4>Results</h4>The incidence of the mortality rate was 2.26 (95%CI: 1.9-2.6) per 100-person day observation. The independent predictors of time to death were age above 65 years (AHR:3.49, 95%CI:1.63, 7.48), severe TBI (AHR: 8.8, 95%CI:5.13, 15.0), moderate TBI (AHR:3, 95%CI:1.73,5.31), hypotension (AHR:1.72, 95%CI: 1.11,2.66), hypoxia (AHR:1.92, 95%CI: 1.33,2.76), hyperthermia (AHR:1.8, 95%CI: 1.23,2.63) and hypoglycemic (AHR:1.94, 95%CI: 1.34, 2.81) positively associated with mortality, while underwent neurosurgery was negatively associated with mortality (AHR: 0.25, 95% CI: 0.11,0.53).<h4>Conclusion</h4>The incidence of mortality rate among head injury patients was high. Older age, moderate and severe TBI, hypotension and hypoxia at admission, neurosurgical procedure, and the episode of hyperthermia and hypoglycemia during hospitalization were the independent predictors of mortality among head injury patients. Therefore, intervention to reduce earlier deaths should focus on the prevention of secondary brain insults.
format	article
author	Desalegn Dawit Assele Tigabu Addisu Lendado Merid Assefa Awato Shimelash Bitew Workie Wolde Facha Faltamo
author_facet	Desalegn Dawit Assele Tigabu Addisu Lendado Merid Assefa Awato Shimelash Bitew Workie Wolde Facha Faltamo
author_sort	Desalegn Dawit Assele
title	Incidence and predictors of mortality among patients with head injury admitted to Hawassa University Comprehensive Specialized Hospital, Southern Ethiopia: A retrospective follow-up study.
title_short	Incidence and predictors of mortality among patients with head injury admitted to Hawassa University Comprehensive Specialized Hospital, Southern Ethiopia: A retrospective follow-up study.
title_full	Incidence and predictors of mortality among patients with head injury admitted to Hawassa University Comprehensive Specialized Hospital, Southern Ethiopia: A retrospective follow-up study.
title_fullStr	Incidence and predictors of mortality among patients with head injury admitted to Hawassa University Comprehensive Specialized Hospital, Southern Ethiopia: A retrospective follow-up study.
title_full_unstemmed	Incidence and predictors of mortality among patients with head injury admitted to Hawassa University Comprehensive Specialized Hospital, Southern Ethiopia: A retrospective follow-up study.
title_sort	incidence and predictors of mortality among patients with head injury admitted to hawassa university comprehensive specialized hospital, southern ethiopia: a retrospective follow-up study.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/5bd5e3ece3b1428ba9da045e49a5b00e
work_keys_str_mv	AT desalegndawitassele incidenceandpredictorsofmortalityamongpatientswithheadinjuryadmittedtohawassauniversitycomprehensivespecializedhospitalsouthernethiopiaaretrospectivefollowupstudy AT tigabuaddisulendado incidenceandpredictorsofmortalityamongpatientswithheadinjuryadmittedtohawassauniversitycomprehensivespecializedhospitalsouthernethiopiaaretrospectivefollowupstudy AT meridassefaawato incidenceandpredictorsofmortalityamongpatientswithheadinjuryadmittedtohawassauniversitycomprehensivespecializedhospitalsouthernethiopiaaretrospectivefollowupstudy AT shimelashbitewworkie incidenceandpredictorsofmortalityamongpatientswithheadinjuryadmittedtohawassauniversitycomprehensivespecializedhospitalsouthernethiopiaaretrospectivefollowupstudy AT woldefachafaltamo incidenceandpredictorsofmortalityamongpatientswithheadinjuryadmittedtohawassauniversitycomprehensivespecializedhospitalsouthernethiopiaaretrospectivefollowupstudy
_version_	1718374645970763776

Incidence and predictors of mortality among patients with head injury admitted to Hawassa University Comprehensive Specialized Hospital, Southern Ethiopia: A retrospective follow-up study.

Ejemplares similares