EXERCISE TOLERANCE TEST AS A SCREENING TOOL FOR CORONARY ARTERY DISEASE IN ASYMPTOMATIC ADULTS

Objective: To determine the screening efficacy of exercise tolerance test in the diagnosis of coronary artery disease in asymptomatic physically active adults. Study Design: Hospital-based cross-sectional validation study. Place and Duration of Study: Department of Medicine, Combined Military...

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Autores principales:	Wasif Anwar, Rana Shahid, Nadeem Ahmed Sheikh, Mohsin Saif
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2020
Materias:	atherosclerosis coronary artery disease mass screening Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/5be15db8c02449969e8da0c23357777c
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spelling	oai:doaj.org-article:5be15db8c02449969e8da0c23357777c2021-12-02T19:18:22ZEXERCISE TOLERANCE TEST AS A SCREENING TOOL FOR CORONARY ARTERY DISEASE IN ASYMPTOMATIC ADULTS0030-96482411-8842https://doaj.org/article/5be15db8c02449969e8da0c23357777c2020-10-01T00:00:00Zhttps://pafmj.org/index.php/PAFMJ/article/view/5552https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To determine the screening efficacy of exercise tolerance test in the diagnosis of coronary artery disease in asymptomatic physically active adults. Study Design: Hospital-based cross-sectional validation study. Place and Duration of Study: Department of Medicine, Combined Military Hospital Mangla Cantonment, from Jan 2019 to Nov 2019. Methodology: Eight Hundred and Four patients fulfilling the inclusion criteria were included in study after obtaining informed written consent. All the enrolled subjects underwent an exercise tolerance test. Those subjects who had a normal exercise tolerance test were not assessed further and those who had an abnormal or inconclusive exercise tolerance test were referred to Armed Forces Institute of Cardiology/National Institute of Heart Diseases for coronary angiography. A database was maintained and used for further analysis. Results: Exercise tolerance test positivity is very low in asymptomatic young and active males, which was established to be 9% in our study. Similarly it was found that the positive predictive value of an abnormal exercise tolerance test result is also unacceptably low i.e. 18%. Conclusion: The diagnostic yield of exercise tolerance test remains low in view of a very high rate of false positive results, technical & procedural shortfalls and ethical constraints of subjecting asymptomatic persons to invasive and expensive coronary angiography.Wasif AnwarRana ShahidNadeem Ahmed SheikhMohsin SaifArmy Medical College Rawalpindiarticleatherosclerosiscoronary artery diseasemass screeningMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 70, Iss 5, Pp 1294-1299 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	atherosclerosis coronary artery disease mass screening Medicine R Medicine (General) R5-920
spellingShingle	atherosclerosis coronary artery disease mass screening Medicine R Medicine (General) R5-920 Wasif Anwar Rana Shahid Nadeem Ahmed Sheikh Mohsin Saif EXERCISE TOLERANCE TEST AS A SCREENING TOOL FOR CORONARY ARTERY DISEASE IN ASYMPTOMATIC ADULTS
description	Objective: To determine the screening efficacy of exercise tolerance test in the diagnosis of coronary artery disease in asymptomatic physically active adults. Study Design: Hospital-based cross-sectional validation study. Place and Duration of Study: Department of Medicine, Combined Military Hospital Mangla Cantonment, from Jan 2019 to Nov 2019. Methodology: Eight Hundred and Four patients fulfilling the inclusion criteria were included in study after obtaining informed written consent. All the enrolled subjects underwent an exercise tolerance test. Those subjects who had a normal exercise tolerance test were not assessed further and those who had an abnormal or inconclusive exercise tolerance test were referred to Armed Forces Institute of Cardiology/National Institute of Heart Diseases for coronary angiography. A database was maintained and used for further analysis. Results: Exercise tolerance test positivity is very low in asymptomatic young and active males, which was established to be 9% in our study. Similarly it was found that the positive predictive value of an abnormal exercise tolerance test result is also unacceptably low i.e. 18%. Conclusion: The diagnostic yield of exercise tolerance test remains low in view of a very high rate of false positive results, technical & procedural shortfalls and ethical constraints of subjecting asymptomatic persons to invasive and expensive coronary angiography.
format	article
author	Wasif Anwar Rana Shahid Nadeem Ahmed Sheikh Mohsin Saif
author_facet	Wasif Anwar Rana Shahid Nadeem Ahmed Sheikh Mohsin Saif
author_sort	Wasif Anwar
title	EXERCISE TOLERANCE TEST AS A SCREENING TOOL FOR CORONARY ARTERY DISEASE IN ASYMPTOMATIC ADULTS
title_short	EXERCISE TOLERANCE TEST AS A SCREENING TOOL FOR CORONARY ARTERY DISEASE IN ASYMPTOMATIC ADULTS
title_full	EXERCISE TOLERANCE TEST AS A SCREENING TOOL FOR CORONARY ARTERY DISEASE IN ASYMPTOMATIC ADULTS
title_fullStr	EXERCISE TOLERANCE TEST AS A SCREENING TOOL FOR CORONARY ARTERY DISEASE IN ASYMPTOMATIC ADULTS
title_full_unstemmed	EXERCISE TOLERANCE TEST AS A SCREENING TOOL FOR CORONARY ARTERY DISEASE IN ASYMPTOMATIC ADULTS
title_sort	exercise tolerance test as a screening tool for coronary artery disease in asymptomatic adults
publisher	Army Medical College Rawalpindi
publishDate	2020
url	https://doaj.org/article/5be15db8c02449969e8da0c23357777c
work_keys_str_mv	AT wasifanwar exercisetolerancetestasascreeningtoolforcoronaryarterydiseaseinasymptomaticadults AT ranashahid exercisetolerancetestasascreeningtoolforcoronaryarterydiseaseinasymptomaticadults AT nadeemahmedsheikh exercisetolerancetestasascreeningtoolforcoronaryarterydiseaseinasymptomaticadults AT mohsinsaif exercisetolerancetestasascreeningtoolforcoronaryarterydiseaseinasymptomaticadults
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EXERCISE TOLERANCE TEST AS A SCREENING TOOL FOR CORONARY ARTERY DISEASE IN ASYMPTOMATIC ADULTS

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