Rapid eye movement sleep and slow wave sleep rebounded and related factors during positive airway pressure therapy

Abstract This study aimed to investigate the clinical characteristics and predictors of increased rapid eye movement (REM) sleep or slow wave sleep (SWS) in patients with obstructive sleep apnea (OSA) following positive airway pressure (PAP) therapy. The study retrospectively analyzed data from pati...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Jin-Xiang Cheng, Jiafeng Ren, Jian Qiu, Yingcong Jiang, Xianchao Zhao, Shuyu Sun, Changjun Su
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/5bf023037ee4427bacf84dfb8f70a4e5
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:5bf023037ee4427bacf84dfb8f70a4e5
record_format	dspace
spelling	oai:doaj.org-article:5bf023037ee4427bacf84dfb8f70a4e52021-12-02T18:15:33ZRapid eye movement sleep and slow wave sleep rebounded and related factors during positive airway pressure therapy10.1038/s41598-021-87149-32045-2322https://doaj.org/article/5bf023037ee4427bacf84dfb8f70a4e52021-04-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-87149-3https://doaj.org/toc/2045-2322Abstract This study aimed to investigate the clinical characteristics and predictors of increased rapid eye movement (REM) sleep or slow wave sleep (SWS) in patients with obstructive sleep apnea (OSA) following positive airway pressure (PAP) therapy. The study retrospectively analyzed data from patients with OSA who underwent both diagnostic polysomnography (PSG) and pressure titration PSG at the Tangdu Hospital Sleep Medicine Center from 2011–2016. Paired diagnostic PSG and pressure titration studies from 501 patients were included. REM rebound was predicted by a higher oxygen desaturation index, lower REM proportion, higher arousal index, lower mean pulse oxygen saturation (SpO2), higher Epworth sleepiness score and younger age (adjusted R2 = 0.482). The SWS rebound was predicted by a longer total duration of apneas and hypopneas, lower N3 duration, lower SpO2 nadir, lower REM proportion in diagnostic PSG and younger age (adjusted R2 = 0.286). Patients without REM rebound or SWS rebound had a high probability of comorbidities with insomnia and mood complaints. Some parameters (subjective and objective insomnia, excessive daytime sleepiness, age and OSA severity) indicate changes in REM sleep and SWS between diagnostic and titration PSG tests. Treatment of insomnia and mood disorders in patients with OSA may helpful to improve the use PAP.Jin-Xiang ChengJiafeng RenJian QiuYingcong JiangXianchao ZhaoShuyu SunChangjun SuNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Jin-Xiang Cheng Jiafeng Ren Jian Qiu Yingcong Jiang Xianchao Zhao Shuyu Sun Changjun Su Rapid eye movement sleep and slow wave sleep rebounded and related factors during positive airway pressure therapy
description	Abstract This study aimed to investigate the clinical characteristics and predictors of increased rapid eye movement (REM) sleep or slow wave sleep (SWS) in patients with obstructive sleep apnea (OSA) following positive airway pressure (PAP) therapy. The study retrospectively analyzed data from patients with OSA who underwent both diagnostic polysomnography (PSG) and pressure titration PSG at the Tangdu Hospital Sleep Medicine Center from 2011–2016. Paired diagnostic PSG and pressure titration studies from 501 patients were included. REM rebound was predicted by a higher oxygen desaturation index, lower REM proportion, higher arousal index, lower mean pulse oxygen saturation (SpO2), higher Epworth sleepiness score and younger age (adjusted R2 = 0.482). The SWS rebound was predicted by a longer total duration of apneas and hypopneas, lower N3 duration, lower SpO2 nadir, lower REM proportion in diagnostic PSG and younger age (adjusted R2 = 0.286). Patients without REM rebound or SWS rebound had a high probability of comorbidities with insomnia and mood complaints. Some parameters (subjective and objective insomnia, excessive daytime sleepiness, age and OSA severity) indicate changes in REM sleep and SWS between diagnostic and titration PSG tests. Treatment of insomnia and mood disorders in patients with OSA may helpful to improve the use PAP.
format	article
author	Jin-Xiang Cheng Jiafeng Ren Jian Qiu Yingcong Jiang Xianchao Zhao Shuyu Sun Changjun Su
author_facet	Jin-Xiang Cheng Jiafeng Ren Jian Qiu Yingcong Jiang Xianchao Zhao Shuyu Sun Changjun Su
author_sort	Jin-Xiang Cheng
title	Rapid eye movement sleep and slow wave sleep rebounded and related factors during positive airway pressure therapy
title_short	Rapid eye movement sleep and slow wave sleep rebounded and related factors during positive airway pressure therapy
title_full	Rapid eye movement sleep and slow wave sleep rebounded and related factors during positive airway pressure therapy
title_fullStr	Rapid eye movement sleep and slow wave sleep rebounded and related factors during positive airway pressure therapy
title_full_unstemmed	Rapid eye movement sleep and slow wave sleep rebounded and related factors during positive airway pressure therapy
title_sort	rapid eye movement sleep and slow wave sleep rebounded and related factors during positive airway pressure therapy
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/5bf023037ee4427bacf84dfb8f70a4e5
work_keys_str_mv	AT jinxiangcheng rapideyemovementsleepandslowwavesleepreboundedandrelatedfactorsduringpositiveairwaypressuretherapy AT jiafengren rapideyemovementsleepandslowwavesleepreboundedandrelatedfactorsduringpositiveairwaypressuretherapy AT jianqiu rapideyemovementsleepandslowwavesleepreboundedandrelatedfactorsduringpositiveairwaypressuretherapy AT yingcongjiang rapideyemovementsleepandslowwavesleepreboundedandrelatedfactorsduringpositiveairwaypressuretherapy AT xianchaozhao rapideyemovementsleepandslowwavesleepreboundedandrelatedfactorsduringpositiveairwaypressuretherapy AT shuyusun rapideyemovementsleepandslowwavesleepreboundedandrelatedfactorsduringpositiveairwaypressuretherapy AT changjunsu rapideyemovementsleepandslowwavesleepreboundedandrelatedfactorsduringpositiveairwaypressuretherapy
_version_	1718378334291755008

Rapid eye movement sleep and slow wave sleep rebounded and related factors during positive airway pressure therapy

Ejemplares similares