Influence of sevoflurane or propofol anaesthesia on oxidative stress parameters in dogs with early-stage myxomatous mitral valve degeneration. A preliminary study

The aim of this study was to investigate the effects of total intravenous anaesthesia with propofol and anaesthesia induced with propofol and maintained with sevoflurane on oxidative stress parameters in dogs with early-stage myxomatous mitral valve degeneration (MMVD). Sixteen client-owned dogs wit...

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Autores principales:	Katerina Tomsič, Alenka Nemec Svete, Ana Nemec, Aleksandra Domanjko Petrič, Tomaž Vovk, Alenka Seliškar
Formato:	article
Lenguaje:	EN
Publicado:	Sciendo 2018
Materias:	dogs myxomatous mitral valve disease oxidative stress propofol sevoflurane Veterinary medicine SF600-1100
Acceso en línea:	https://doaj.org/article/5bf0a7d694f54ab4a3a18b748d6f7d5f
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spelling	oai:doaj.org-article:5bf0a7d694f54ab4a3a18b748d6f7d5f2021-11-17T21:27:52ZInfluence of sevoflurane or propofol anaesthesia on oxidative stress parameters in dogs with early-stage myxomatous mitral valve degeneration. A preliminary study1820-744810.2478/acve-2018-0003https://doaj.org/article/5bf0a7d694f54ab4a3a18b748d6f7d5f2018-03-01T00:00:00Zhttps://doi.org/10.2478/acve-2018-0003https://doaj.org/toc/1820-7448The aim of this study was to investigate the effects of total intravenous anaesthesia with propofol and anaesthesia induced with propofol and maintained with sevoflurane on oxidative stress parameters in dogs with early-stage myxomatous mitral valve degeneration (MMVD). Sixteen client-owned dogs with early stage MMVD that required periodontal treatment were included in the study. After induction with propofol, anaesthesia was maintained with propofol (group P) or sevoflurane (group PS). Blood samples for determination of vitamin E, superoxide dismutase, glutathione peroxidase and malondialdehyde were collected before premedication, 5 and 60 minutes and 6 hours after induction to anaesthesia. There were no significant differences between groups in any of the oxidative stress parameters at each sampling time. Compared to basal values, vitamin E concentration decreased significantly during anaesthesia in both groups and glutathione peroxidase activity increased 60 minutes after induction to anaesthesia in PS group. Anaesthesia with propofol or with propofol and sevoflurane did not have any significant impact on oxidative stress parameters in dogs with early stage MMVD. In terms of oxidative stress, both protocols may be equally safely used in dogs with early stage MMVD.Katerina TomsičAlenka Nemec SveteAna NemecAleksandra Domanjko PetričTomaž VovkAlenka SeliškarSciendoarticledogsmyxomatous mitral valve diseaseoxidative stresspropofolsevofluraneVeterinary medicineSF600-1100ENActa Veterinaria, Vol 68, Iss 1, Pp 32-42 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	dogs myxomatous mitral valve disease oxidative stress propofol sevoflurane Veterinary medicine SF600-1100
spellingShingle	dogs myxomatous mitral valve disease oxidative stress propofol sevoflurane Veterinary medicine SF600-1100 Katerina Tomsič Alenka Nemec Svete Ana Nemec Aleksandra Domanjko Petrič Tomaž Vovk Alenka Seliškar Influence of sevoflurane or propofol anaesthesia on oxidative stress parameters in dogs with early-stage myxomatous mitral valve degeneration. A preliminary study
description	The aim of this study was to investigate the effects of total intravenous anaesthesia with propofol and anaesthesia induced with propofol and maintained with sevoflurane on oxidative stress parameters in dogs with early-stage myxomatous mitral valve degeneration (MMVD). Sixteen client-owned dogs with early stage MMVD that required periodontal treatment were included in the study. After induction with propofol, anaesthesia was maintained with propofol (group P) or sevoflurane (group PS). Blood samples for determination of vitamin E, superoxide dismutase, glutathione peroxidase and malondialdehyde were collected before premedication, 5 and 60 minutes and 6 hours after induction to anaesthesia. There were no significant differences between groups in any of the oxidative stress parameters at each sampling time. Compared to basal values, vitamin E concentration decreased significantly during anaesthesia in both groups and glutathione peroxidase activity increased 60 minutes after induction to anaesthesia in PS group. Anaesthesia with propofol or with propofol and sevoflurane did not have any significant impact on oxidative stress parameters in dogs with early stage MMVD. In terms of oxidative stress, both protocols may be equally safely used in dogs with early stage MMVD.
format	article
author	Katerina Tomsič Alenka Nemec Svete Ana Nemec Aleksandra Domanjko Petrič Tomaž Vovk Alenka Seliškar
author_facet	Katerina Tomsič Alenka Nemec Svete Ana Nemec Aleksandra Domanjko Petrič Tomaž Vovk Alenka Seliškar
author_sort	Katerina Tomsič
title	Influence of sevoflurane or propofol anaesthesia on oxidative stress parameters in dogs with early-stage myxomatous mitral valve degeneration. A preliminary study
title_short	Influence of sevoflurane or propofol anaesthesia on oxidative stress parameters in dogs with early-stage myxomatous mitral valve degeneration. A preliminary study
title_full	Influence of sevoflurane or propofol anaesthesia on oxidative stress parameters in dogs with early-stage myxomatous mitral valve degeneration. A preliminary study
title_fullStr	Influence of sevoflurane or propofol anaesthesia on oxidative stress parameters in dogs with early-stage myxomatous mitral valve degeneration. A preliminary study
title_full_unstemmed	Influence of sevoflurane or propofol anaesthesia on oxidative stress parameters in dogs with early-stage myxomatous mitral valve degeneration. A preliminary study
title_sort	influence of sevoflurane or propofol anaesthesia on oxidative stress parameters in dogs with early-stage myxomatous mitral valve degeneration. a preliminary study
publisher	Sciendo
publishDate	2018
url	https://doaj.org/article/5bf0a7d694f54ab4a3a18b748d6f7d5f
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Influence of sevoflurane or propofol anaesthesia on oxidative stress parameters in dogs with early-stage myxomatous mitral valve degeneration. A preliminary study

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