A high-speed search engine pLink 2 with systematic evaluation for proteome-scale identification of cross-linked peptides
The identification of cross-linked peptides at a proteome scale for interactome analyses represents a complex challenge. Here the authors report an efficient and reliable search engine pLink 2 for proteome-scale cross-linking mass spectrometry analyses, and demonstrate how to systematically evaluate...
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Main Authors: | Zhen-Lin Chen, Jia-Ming Meng, Yong Cao, Ji-Li Yin, Run-Qian Fang, Sheng-Bo Fan, Chao Liu, Wen-Feng Zeng, Yue-He Ding, Dan Tan, Long Wu, Wen-Jing Zhou, Hao Chi, Rui-Xiang Sun, Meng-Qiu Dong, Si-Min He |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2019
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Online Access: | https://doaj.org/article/5bf1da56fec7495f8b611bdf3f8aef38 |
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