A high-speed search engine pLink 2 with systematic evaluation for proteome-scale identification of cross-linked peptides

A high-speed search engine pLink 2 with systematic evaluation for proteome-scale identification of cross-linked peptides

The identification of cross-linked peptides at a proteome scale for interactome analyses represents a complex challenge. Here the authors report an efficient and reliable search engine pLink 2 for proteome-scale cross-linking mass spectrometry analyses, and demonstrate how to systematically evaluate...

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Main Authors: Zhen-Lin Chen, Jia-Ming Meng, Yong Cao, Ji-Li Yin, Run-Qian Fang, Sheng-Bo Fan, Chao Liu, Wen-Feng Zeng, Yue-He Ding, Dan Tan, Long Wu, Wen-Jing Zhou, Hao Chi, Rui-Xiang Sun, Meng-Qiu Dong, Si-Min He
Format: article
Language:EN
Published: Nature Portfolio 2019
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Science
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Online Access:https://doaj.org/article/5bf1da56fec7495f8b611bdf3f8aef38
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https://doaj.org/article/5bf1da56fec7495f8b611bdf3f8aef38

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