Rapid processing of fearful faces relies on the right amygdala: evidence from individuals undergoing unilateral temporal lobectomy

Abstract Facial expressions of emotions have been shown to modulate early ERP components, in particular the N170. The underlying anatomical structure producing these early effects are unclear. In this study, we examined the N170 enhancement for fearful expressions in healthy controls as well as epil...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: David Framorando, Eleanor Moses, Lore Legrand, Margitta Seeck, Alan J. Pegna
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
R
Q
Acceso en línea:https://doaj.org/article/5bf243eed99a417580fbd91cef7604c0
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:5bf243eed99a417580fbd91cef7604c0
record_format dspace
spelling oai:doaj.org-article:5bf243eed99a417580fbd91cef7604c02021-12-02T14:01:20ZRapid processing of fearful faces relies on the right amygdala: evidence from individuals undergoing unilateral temporal lobectomy10.1038/s41598-020-80054-12045-2322https://doaj.org/article/5bf243eed99a417580fbd91cef7604c02021-01-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-80054-1https://doaj.org/toc/2045-2322Abstract Facial expressions of emotions have been shown to modulate early ERP components, in particular the N170. The underlying anatomical structure producing these early effects are unclear. In this study, we examined the N170 enhancement for fearful expressions in healthy controls as well as epileptic patients after unilateral left or right amygdala resection. We observed a greater N170 for fearful faces in healthy participants as well as in individuals with left amygdala resections. By contrast, the effect was not observed in patients who had undergone surgery in which the right amygdala had been removed. This result demonstrates that the amygdala produces an early brain response to fearful faces. This early response relies specifically on the right amygdala and occurs at around 170 ms. It is likely that such increases are due to a heightened response of the extrastriate cortex that occurs through rapid amygdalofugal projections to the visual areas.David FramorandoEleanor MosesLore LegrandMargitta SeeckAlan J. PegnaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
David Framorando
Eleanor Moses
Lore Legrand
Margitta Seeck
Alan J. Pegna
Rapid processing of fearful faces relies on the right amygdala: evidence from individuals undergoing unilateral temporal lobectomy
description Abstract Facial expressions of emotions have been shown to modulate early ERP components, in particular the N170. The underlying anatomical structure producing these early effects are unclear. In this study, we examined the N170 enhancement for fearful expressions in healthy controls as well as epileptic patients after unilateral left or right amygdala resection. We observed a greater N170 for fearful faces in healthy participants as well as in individuals with left amygdala resections. By contrast, the effect was not observed in patients who had undergone surgery in which the right amygdala had been removed. This result demonstrates that the amygdala produces an early brain response to fearful faces. This early response relies specifically on the right amygdala and occurs at around 170 ms. It is likely that such increases are due to a heightened response of the extrastriate cortex that occurs through rapid amygdalofugal projections to the visual areas.
format article
author David Framorando
Eleanor Moses
Lore Legrand
Margitta Seeck
Alan J. Pegna
author_facet David Framorando
Eleanor Moses
Lore Legrand
Margitta Seeck
Alan J. Pegna
author_sort David Framorando
title Rapid processing of fearful faces relies on the right amygdala: evidence from individuals undergoing unilateral temporal lobectomy
title_short Rapid processing of fearful faces relies on the right amygdala: evidence from individuals undergoing unilateral temporal lobectomy
title_full Rapid processing of fearful faces relies on the right amygdala: evidence from individuals undergoing unilateral temporal lobectomy
title_fullStr Rapid processing of fearful faces relies on the right amygdala: evidence from individuals undergoing unilateral temporal lobectomy
title_full_unstemmed Rapid processing of fearful faces relies on the right amygdala: evidence from individuals undergoing unilateral temporal lobectomy
title_sort rapid processing of fearful faces relies on the right amygdala: evidence from individuals undergoing unilateral temporal lobectomy
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/5bf243eed99a417580fbd91cef7604c0
work_keys_str_mv AT davidframorando rapidprocessingoffearfulfacesreliesontherightamygdalaevidencefromindividualsundergoingunilateraltemporallobectomy
AT eleanormoses rapidprocessingoffearfulfacesreliesontherightamygdalaevidencefromindividualsundergoingunilateraltemporallobectomy
AT lorelegrand rapidprocessingoffearfulfacesreliesontherightamygdalaevidencefromindividualsundergoingunilateraltemporallobectomy
AT margittaseeck rapidprocessingoffearfulfacesreliesontherightamygdalaevidencefromindividualsundergoingunilateraltemporallobectomy
AT alanjpegna rapidprocessingoffearfulfacesreliesontherightamygdalaevidencefromindividualsundergoingunilateraltemporallobectomy
_version_ 1718392201163046912