Heart failure and cognitive impairment: Challenges and opportunities

George A Heckman, Christopher J Patterson, Catherine Demers, Joye St.Onge, Irene D Turpie, Robert S McKelvieDepartment of Medicine, McMaster University, Hamilton, Ontario, CanadaAbstract: As populations age, heart failure (HF) is becoming increasingly common, and in addition to a high burden of morb...

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Autores principales:	George A Heckman, Christopher J Patterson, Catherine Demers, Joye St.Onge, Irene D Turpie, Robert S McKelvie
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2007
Materias:	Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/5bf43e6ba85e449e834666395623cd97
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spelling	oai:doaj.org-article:5bf43e6ba85e449e834666395623cd972021-12-02T00:36:26ZHeart failure and cognitive impairment: Challenges and opportunities1178-1998https://doaj.org/article/5bf43e6ba85e449e834666395623cd972007-07-01T00:00:00Zhttps://www.dovepress.com/heart-failure-and-cognitive-impairment-challenges-and-opportunities-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998George A Heckman, Christopher J Patterson, Catherine Demers, Joye St.Onge, Irene D Turpie, Robert S McKelvieDepartment of Medicine, McMaster University, Hamilton, Ontario, CanadaAbstract: As populations age, heart failure (HF) is becoming increasingly common, and in addition to a high burden of morbidity and mortality, HF has an enormous financial impact. Though disproportionately affected by HF, the elderly are less likely to receive recommended therapies, in part because clinical trials of HF therapy have ignored outcomes of importance to this population, including impaired cognitive function (ICF). HF is associated with ICF, manifested primarily as delirium in hospitalized patients, or as mild cognitive impairment or dementia in otherwise stable outpatients. This association is likely the result of shared risk factors, as well as perfusion and rheological abnormalities that occur in patients with HF. Evidence suggests that these abnormalities may be partially reversible with standard HF therapy. The clinical consequences of ICF in HF patients are significant. Clinicians should consider becoming familiar with screening instruments for ICF, including delirium and dementia, in order to identify patients at risk of nonadherence to HF therapy and related adverse consequences. Preliminary evidence suggests that optimal HF therapy in elderly patients may preserve or even improve cognitive function, though the impact on related outcomes remains to be determined.Keywords: heart failure, mild cognitive impairment, delirium, dementia, elderlyGeorge A HeckmanChristopher J PattersonCatherine DemersJoye St.OngeIrene D TurpieRobert S McKelvieDove Medical PressarticleGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 2, Pp 209-218 (2007)
institution	DOAJ
collection	DOAJ
language	EN
topic	Geriatrics RC952-954.6
spellingShingle	Geriatrics RC952-954.6 George A Heckman Christopher J Patterson Catherine Demers Joye St.Onge Irene D Turpie Robert S McKelvie Heart failure and cognitive impairment: Challenges and opportunities
description	George A Heckman, Christopher J Patterson, Catherine Demers, Joye St.Onge, Irene D Turpie, Robert S McKelvieDepartment of Medicine, McMaster University, Hamilton, Ontario, CanadaAbstract: As populations age, heart failure (HF) is becoming increasingly common, and in addition to a high burden of morbidity and mortality, HF has an enormous financial impact. Though disproportionately affected by HF, the elderly are less likely to receive recommended therapies, in part because clinical trials of HF therapy have ignored outcomes of importance to this population, including impaired cognitive function (ICF). HF is associated with ICF, manifested primarily as delirium in hospitalized patients, or as mild cognitive impairment or dementia in otherwise stable outpatients. This association is likely the result of shared risk factors, as well as perfusion and rheological abnormalities that occur in patients with HF. Evidence suggests that these abnormalities may be partially reversible with standard HF therapy. The clinical consequences of ICF in HF patients are significant. Clinicians should consider becoming familiar with screening instruments for ICF, including delirium and dementia, in order to identify patients at risk of nonadherence to HF therapy and related adverse consequences. Preliminary evidence suggests that optimal HF therapy in elderly patients may preserve or even improve cognitive function, though the impact on related outcomes remains to be determined.Keywords: heart failure, mild cognitive impairment, delirium, dementia, elderly
format	article
author	George A Heckman Christopher J Patterson Catherine Demers Joye St.Onge Irene D Turpie Robert S McKelvie
author_facet	George A Heckman Christopher J Patterson Catherine Demers Joye St.Onge Irene D Turpie Robert S McKelvie
author_sort	George A Heckman
title	Heart failure and cognitive impairment: Challenges and opportunities
title_short	Heart failure and cognitive impairment: Challenges and opportunities
title_full	Heart failure and cognitive impairment: Challenges and opportunities
title_fullStr	Heart failure and cognitive impairment: Challenges and opportunities
title_full_unstemmed	Heart failure and cognitive impairment: Challenges and opportunities
title_sort	heart failure and cognitive impairment: challenges and opportunities
publisher	Dove Medical Press
publishDate	2007
url	https://doaj.org/article/5bf43e6ba85e449e834666395623cd97
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Heart failure and cognitive impairment: Challenges and opportunities

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