Transition metal ion FRET uncovers K+ regulation of a neurotransmitter/sodium symporter

The neurotransmitter transporter SERT counter transport K+ to transport serotonin. Here the authors show that the activity of the prokaryotic orthologue LeuT is also modulated by this cation, suggesting a general regulatory role for K+on neutrotrasmitter:sodium symporters function.

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Detalles Bibliográficos
Autores principales:	Christian B. Billesbølle, Jonas S. Mortensen, Azmat Sohail, Solveig G. Schmidt, Lei Shi, Harald H. Sitte, Ulrik Gether, Claus J. Loland
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/5c07a915d81b45039bdbbb7f2201b43f
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spelling	oai:doaj.org-article:5c07a915d81b45039bdbbb7f2201b43f2021-12-02T15:35:01ZTransition metal ion FRET uncovers K+ regulation of a neurotransmitter/sodium symporter10.1038/ncomms127552041-1723https://doaj.org/article/5c07a915d81b45039bdbbb7f2201b43f2016-09-01T00:00:00Zhttps://doi.org/10.1038/ncomms12755https://doaj.org/toc/2041-1723The neurotransmitter transporter SERT counter transport K+ to transport serotonin. Here the authors show that the activity of the prokaryotic orthologue LeuT is also modulated by this cation, suggesting a general regulatory role for K+on neutrotrasmitter:sodium symporters function.Christian B. BillesbølleJonas S. MortensenAzmat SohailSolveig G. SchmidtLei ShiHarald H. SitteUlrik GetherClaus J. LolandNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Christian B. Billesbølle Jonas S. Mortensen Azmat Sohail Solveig G. Schmidt Lei Shi Harald H. Sitte Ulrik Gether Claus J. Loland Transition metal ion FRET uncovers K+ regulation of a neurotransmitter/sodium symporter
description	The neurotransmitter transporter SERT counter transport K+ to transport serotonin. Here the authors show that the activity of the prokaryotic orthologue LeuT is also modulated by this cation, suggesting a general regulatory role for K+on neutrotrasmitter:sodium symporters function.
format	article
author	Christian B. Billesbølle Jonas S. Mortensen Azmat Sohail Solveig G. Schmidt Lei Shi Harald H. Sitte Ulrik Gether Claus J. Loland
author_facet	Christian B. Billesbølle Jonas S. Mortensen Azmat Sohail Solveig G. Schmidt Lei Shi Harald H. Sitte Ulrik Gether Claus J. Loland
author_sort	Christian B. Billesbølle
title	Transition metal ion FRET uncovers K+ regulation of a neurotransmitter/sodium symporter
title_short	Transition metal ion FRET uncovers K+ regulation of a neurotransmitter/sodium symporter
title_full	Transition metal ion FRET uncovers K+ regulation of a neurotransmitter/sodium symporter
title_fullStr	Transition metal ion FRET uncovers K+ regulation of a neurotransmitter/sodium symporter
title_full_unstemmed	Transition metal ion FRET uncovers K+ regulation of a neurotransmitter/sodium symporter
title_sort	transition metal ion fret uncovers k+ regulation of a neurotransmitter/sodium symporter
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/5c07a915d81b45039bdbbb7f2201b43f
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Transition metal ion FRET uncovers K+ regulation of a neurotransmitter/sodium symporter

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