Hippocampal CA3 transcriptional modules associated with granule cell alterations and cognitive impairment in refractory mesial temporal lobe epilepsy patients

Abstract In about a third of the patients with epilepsy the seizures are not drug-controlled. The current limitation of the antiepileptic drug therapy derives from an insufficient understanding of epilepsy pathophysiology. In order to overcome this situation, it is necessary to consider epilepsy as...

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Autores principales: Silvia Yumi Bando, Fernanda Bernardi Bertonha, Luciana Ramalho Pimentel-Silva, João Gabriel Mansano de Oliveira, Marco Antonio Duarte Carneiro, Mariana Hiromi Manoel Oku, Hung-Tzu Wen, Luiz Henrique Martins Castro, Carlos Alberto Moreira-Filho
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/5c0f18538296486aa81aab8bc692ee65
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