Prostaglandin EP2 receptor antagonist ameliorates neuroinflammation in a two-hit mouse model of Alzheimer’s disease

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Prostaglandin EP2 receptor antagonist ameliorates neuroinflammation in a two-hit mouse model of Alzheimer’s disease

Abstract Background Alzheimer’s disease (AD) causes substantial medical and societal burden with no therapies ameliorating cognitive deficits. Centralized pathologies involving amyloids, neurofibrillary tangles, and neuroinflammatory pathways are being investigated to identify disease-modifying targ...

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Autores principales:	Avijit Banik, Radhika Amaradhi, Daniel Lee, Michael Sau, Wenyi Wang, Raymond Dingledine, Thota Ganesh
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Two-hit 5xFAD EP2 Lipopolysaccharide TG11-77.HCl Neuroinflammation Microgliosis Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/5c1524c61ee446028a162ba57509e1d9
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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