Molecular level detection and localization of mechanical damage in collagen enabled by collagen hybridizing peptides

Collagen denaturation is thought to occur during tissue mechanical damage, but its role in damage initiation is still unclear. Here, the authors use a collagen hybridizing peptide to provide insights into the molecular mechanisms leading to collagen unfolding during tendon mechanical stretch.

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Autores principales:	Jared L. Zitnay, Yang Li, Zhao Qin, Boi Hoa San, Baptiste Depalle, Shawn P. Reese, Markus J. Buehler, S. Michael Yu, Jeffrey A. Weiss
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/5c1f37183ded448ab5837d2f669f885c
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spelling	oai:doaj.org-article:5c1f37183ded448ab5837d2f669f885c2021-12-02T14:42:44ZMolecular level detection and localization of mechanical damage in collagen enabled by collagen hybridizing peptides10.1038/ncomms149132041-1723https://doaj.org/article/5c1f37183ded448ab5837d2f669f885c2017-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms14913https://doaj.org/toc/2041-1723Collagen denaturation is thought to occur during tissue mechanical damage, but its role in damage initiation is still unclear. Here, the authors use a collagen hybridizing peptide to provide insights into the molecular mechanisms leading to collagen unfolding during tendon mechanical stretch.Jared L. ZitnayYang LiZhao QinBoi Hoa SanBaptiste DepalleShawn P. ReeseMarkus J. BuehlerS. Michael YuJeffrey A. WeissNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jared L. Zitnay Yang Li Zhao Qin Boi Hoa San Baptiste Depalle Shawn P. Reese Markus J. Buehler S. Michael Yu Jeffrey A. Weiss Molecular level detection and localization of mechanical damage in collagen enabled by collagen hybridizing peptides
description	Collagen denaturation is thought to occur during tissue mechanical damage, but its role in damage initiation is still unclear. Here, the authors use a collagen hybridizing peptide to provide insights into the molecular mechanisms leading to collagen unfolding during tendon mechanical stretch.
format	article
author	Jared L. Zitnay Yang Li Zhao Qin Boi Hoa San Baptiste Depalle Shawn P. Reese Markus J. Buehler S. Michael Yu Jeffrey A. Weiss
author_facet	Jared L. Zitnay Yang Li Zhao Qin Boi Hoa San Baptiste Depalle Shawn P. Reese Markus J. Buehler S. Michael Yu Jeffrey A. Weiss
author_sort	Jared L. Zitnay
title	Molecular level detection and localization of mechanical damage in collagen enabled by collagen hybridizing peptides
title_short	Molecular level detection and localization of mechanical damage in collagen enabled by collagen hybridizing peptides
title_full	Molecular level detection and localization of mechanical damage in collagen enabled by collagen hybridizing peptides
title_fullStr	Molecular level detection and localization of mechanical damage in collagen enabled by collagen hybridizing peptides
title_full_unstemmed	Molecular level detection and localization of mechanical damage in collagen enabled by collagen hybridizing peptides
title_sort	molecular level detection and localization of mechanical damage in collagen enabled by collagen hybridizing peptides
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/5c1f37183ded448ab5837d2f669f885c
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Molecular level detection and localization of mechanical damage in collagen enabled by collagen hybridizing peptides

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